RT Journal Article
T1 A standard structure for bile acids and derivatives
A1 Meijide del Río, Francisco Ángel
A1 Frutos del Río, Santiago de
A1 Soto Tellini, Victor Hugo
A1 Jover Ramos, Aida
A1 Seijas Vázquez, Julio Antonio
A1 Vázquez Tato, María del Pilar
A1 Fraga López, Francisco
A1 Vázquez Tato, José
K1 Crystal structure
K1 Steroid
K1 Bile acids
AB The crystal structures of two ester compounds (a monomer in its methyl ester form,with anamino isophthalic group, and a dimer in which the two steroid units are linked by a urea bridgerecrystallized from ethyl acetate/methanol) derived from cholic acid are described. Average bondlengths and bond angles from the crystal structures of 26 monomers and four dimers (some of themin several solvents) of bile acids and esters (and derivatives) are used for proposing a standardsteroid nucleus. The hydrogen bond network and conformation of the lateral chain are also discussed.This standardstructure was used to compare with the structures of both progesterone and cholesterol
PB MDPI
YR 2018
FD 2018
LK http://hdl.handle.net/10347/23203
UL http://hdl.handle.net/10347/23203
LA eng
NO Meijide, F.; De Frutos, S.; Soto, V.H.; Jover, A.; Seijas, J.A.; Vázquez-Tato, M.P.; Fraga, F.; Tato, J.V. A Standard Structure for Bile Acids and Derivatives. Crystals 2018, 8, 86
NO The authors thank the Ministerio de Ciencia y Tecnología (Project MAT2013-45657-P) forfinancial support
DS Minerva
RD 29 abr 2026