RT Journal Article
T1 Recent advances in 3D printed cellulose-based wound dressings: A review on in vitro and in vivo achievements
A1 Pita Vilar, María
A1 Concheiro Nine, Ángel Joaquín
A1 Díaz Gómez, Luis
A1 Álvarez Lorenzo, Carmen
K1 3D printing
K1 Cellulose
K1 Nanocellulose
K1 Personalized dressing
K1 Cellulose ether
K1 Diabetic foot ulcer
AB Chronic wounds, especially diabetic ulcers, pose a significant challenge in regenerative medicine. Cellulose derivatives offer remarkable wound management properties, such as effective absorption and retention of wound exudates, maintaining an optimal moisture environment crucial for successful chronic wound regeneration. However, conventional dressings have limited efficacy in managing and healing these types of skin lesions, driving scientists to explore innovative approaches. The emergence of 3D printing has enabled personalized dressings that meet individual patient needs, improving the healing process and patient comfort. Cellulose derivatives meet the demanding requirements for biocompatibility, printability, and biofabrication necessary for 3D printing of biologically active scaffolds. However, the potential applications of nanocellulose and cellulose derivative-based inks for wound regeneration remain largely unexplored. Thus, this review provides a comprehensive overview of recent advancements in cellulose-based inks for 3D printing of personalized wound dressings. The composition and biofabrication approaches of cellulose-based wound dressings are thoroughly discussed, including the functionalization with bioactive molecules and antibiotics for improved wound regeneration. Similarly, the in vitro and in vivo performance of these dressings is extensively examined. In summary, this review aims to highlight the exceptional advantages and diverse applications of 3D printed cellulose-based dressings in personalized wound care
PB Elsevier
SN 0144-8617
YR 2023
FD 2023-08-12
LK http://hdl.handle.net/10347/31012
UL http://hdl.handle.net/10347/31012
LA eng
NO Carbohydrate Polymers 321 (2023) 121298
NO This research was funded by Xunta de Galicia [ED431C 2020/17], MCIN/AEI/10.13039/501100011033 [PID2020-113881RB-I00; PID2021-127493OA-C22] (Spain), and FEDER
DS Minerva
RD 22 abr 2026