RT Journal Article
T1 Histological and histomorphometric study of human palatal mucosa: implications for connective tissue graft harvesting
A1 García-Caballero, Lucía
A1 Gándara Cortés, Marina
A1 Cepeda Emiliani, Alfonso
A1 Gallego, Rosalía
A1 Gude, Francisco
A1 Suárez Quintanilla, Juan
A1 Ramos Barbosa, Isabel
A1 Blanco Carrión, Juan
K1 Connective tissue grafts
K1 Histology
K1 Histomorphometry
K1 Human palatal mucosa
AB AimsTo analyse the histological structure and histomorphometric characteristics of human hard palatal mucosa in order to determine the donor site of choice for connective tissue grafts from a histological point of view.Materials and MethodsPalatal mucosa samples from six cadaver heads were harvested at four sites: incisal, premolar, molar and tuberosity. Histological and immunohistochemical techniques were performed, as was histomorphometric analysis.ResultsIn the current study, we found that the density and size of cells were higher in the superficial papillary layer, whereas the thickness of the collagen bundles increased in the reticular layer. Excluding the epithelium, the mean percentage of lamina propria (LP) and submucosa (SM) was 37% and 63%, respectively (p < .001). LP thickness showed similar values in the incisal, premolar and molar regions, and a significantly greater thickness in tuberosity (p < .001). The thickness of SM increased from incisal to premolar and molar, disappearing in the tuberosity (p < .001).ConclusionsAs dense connective tissue of LP is the tissue of choice for connective tissue grafts, the best donor site from a histological point of view is tuberosity because it is composed only of a thick LP without the presence of a loose submucosal layer
PB Wiley
SN 0303-6979
YR 2023
FD 2023
LK http://hdl.handle.net/10347/30773
UL http://hdl.handle.net/10347/30773
LA eng
NO García-Caballero, L., Gándara, M., Cepeda-Emiliani, A., Gallego, R., Gude, F., Suárez-Quintanilla, J., Ramos-Barbosa, I., & Blanco-Carrion, J. (2023). Histological   and histomorphometric study of human palatal mucosa: Implications for connective tissue graft harvesting. Journal of Clinical Periodontology, 50(6), 784–795. https://doi.org/10. 1111/jcpe.13800
DS Minerva
RD 24 abr 2026