RT Journal Article T1 Comparison between Sandblasted Acid-Etched and Oxidized Titanium Dental Implants: In Vivo Study A1 Velasco Ortega, Eugenio A1 Ortiz García, Iván A1 Jiménez Guerra, Álvaro A1 Monsalve Guil, Loreto A1 Muñoz Guzón, Fernando María A1 Pérez, Román A. A1 Gil, F. Javier K1 Osseointegration K1 Titanium K1 Implant surface K1 Sandblasted surface K1 Acid-etched surface K1 Oxidized surface AB The surface modifications of titanium dental implants play important roles in the enhancement of osseointegration. The objective of the present study was to test two different implant surface treatments on a rabbit model to investigate the osseointegration. The tested surfaces were: a) acid-etched surface with sandblasting treatment (SA) and b) an oxidized implant surface (OS). The roughness was measured by an interferometeric microscope with white light and the residual stress of the surfaces was measured with X-ray residual stress Bragg–Bentano diffraction. Six New Zealand white rabbits were used for the in vivo study. Implants with the two different surfaces (SA and OS) were inserted in the femoral bone. After 12 weeks of implantation, histological and histomorphometric analyses of the blocks containing the implants and the surrounding bone were performed. All the implants were correctly implanted and no signs of infection were observed. SA and OS surfaces were both surrounded by newly formed trabeculae. Histomorphometric analysis revealed that the bone–implant contact % (BIC) was higher around the SA implants (53.49 ± 8.46) than around the OS implants (50.94 ± 16.42), although there were no significant statistical differences among them. Both implant surfaces (SA and OS) demonstrated a good bone response with significant amounts of newly formed bone along the implant surface after 12 weeks of implantation. These results confirmed the importance of the topography and physico–chemical properties of dental implants in the osseointegration. PB MDPI YR 2019 FD 2019 LK http://hdl.handle.net/10347/20982 UL http://hdl.handle.net/10347/20982 LA eng NO Velasco-Ortega, E., Ortiz-García, I., Jiménez-Guerra, A., Monsalve-Guil, L., Muñoz-Guzón, F., Perez, R. A., & Gil, F. J. (2019). Comparison between sandblasted acid-etched and oxidized titanium dental implants: in vivo study. International journal of molecular sciences, 20(13), 3267. NO The authors are grateful to the Spanish Government and European Union FEDER by the concession of the project RTI2018-098075-B-C22 DS Minerva RD 29 abr 2026