RT Conference_Proceedings
T1 Modelling the production of VFA from proteins by mixed culture fermentations
A1 Regueira López, Alberte
A1 Bevilacqua, Riccardo
A1 Lema Rodicio, Juan Manuel
A1 Mauricio Iglesias, Miguel
A1 Carballa Arcos, Marta
K1 Volatile fatty acids
K1 Metabolic modelling
K1 Protein fermentation
K1 Mixed culture fermentation
AB Mixed-culture fermentations (MCF) are recognised as a valid process to yield added-value products from organic wastes in the form of volatile fatty acids (VFA). The use of mixed cultures is attractive due to their economical and operational advantages (e.g. no sterilisation is needed). However, they also pose a fundamental challenge: they are complex and their regulation mechanisms remain still unclear. One of the main limitations of the process is its low product selectivity: the productivity of the different VFA is highly dependant on operational conditions (e.g. pH, retention time or feeding characteristics). In consequence, developing bioprocesses based on this technology remains a challenging task. In this context, we aim at establishing a model-based methodology for developing novel bioprocess using MCF. The emphasis is placed on two aspects: to reach a high productivity and a high selectivity on the desired VFA(s). The improvement of selectivity is carried out by means of a metabolic energy-based model while the productivity is maximised using a general kinetic-based model
YR 2019
FD 2019-06
LK http://hdl.handle.net/10347/20448
UL http://hdl.handle.net/10347/20448
LA spa
NO The authors would like to acknowledge the support of the Spanish Ministry of Education (FPU14/05457) and ERA-IB-2 project BIOCHEM (PCIN 2016-102) funded by MINECO. The authors belong to the Galician Competitive Research Group ED431C2017/029 and to the CRETUS Stragetic Partnership (AGRUIP2017/01). All these programmes are co-funded by FEDER (UE)
DS Minerva
RD 4 may 2026