RT Journal Article
T1 Differences in Dry Eye Questionnaire Symptoms in Two Different Modalities of Contact Lens Wear: Silicone-Hydrogel in Daily Wear Basis and Overnight Orthokeratology
A1 García Porta, Nery
A1 Rico-del-Viejo, Laura
A1 Martín-Gil, Alba
A1 Carracedo, Gonzalo
A1 Pintor, Jesús
A1 González Méijome, José Manuel
AB Purpose. To compare the ocular surface symptoms and signs in an adult population of silicone-hydrogel (Si-Hy) contact lens (CL) wearers with another modality of CL wear, overnight orthokeratology (OK). Materials and Methods. This was a prospective and comparative study in which 31 myopic subjects were fitted with the same Si-Hy CL and 23 underwent OK treatment for 3 months. Dry eye questionnaire (DEQ) was filled in at the beginning of the study and then after 15 days, 1 month, and 3 months using each CL modality. The tear quality was evaluated with noninvasive tear break-up time. Tear production was measured with Schirmer test. Tear samples were collected with Schirmer strips being frozen to analyze the dinucleotide diadenosine tetraphosphate (Ap4A) concentration with High-Performance Liquid Chromatography (HPLC). Results. After refitting with ortho-k, a reduction in discomfort and dryness symptoms at the end of the day (, ) was observed. No significant changes were observed in Ap4A concentration in any group. Bulbar redness, limbal redness, and conjunctival staining increased significantly in the Si-Hy group (, Kruskal–Wallis test). Conclusion. Discomfort and dryness symptoms at the end of the day are lower in the OK CL group than in the Si-Hy CL group
PB Hindawi
SN 2314-6133
YR 2016
FD 2016
LK http://hdl.handle.net/10347/16305
UL http://hdl.handle.net/10347/16305
LA eng
NO Nery García-Porta, Laura Rico-del-Viejo, Alba Martin-Gil, Gonzalo Carracedo, Jesus Pintor, and José Manuel González-Méijome, “Differences in Dry Eye Questionnaire Symptoms in Two Different Modalities of Contact Lens Wear: Silicone-Hydrogel in Daily Wear Basis and Overnight Orthokeratology,” BioMed Research International, vol. 2016, Article ID 1242845, 9 pages, 2016. doi:10.1155/2016/1242845
NO This work was partially supported bythe Xunta de Galicia by a predoctoral grant of the Plan I2C2011–2015 and the Spanish SAF2013-44416-R and RETICSRD12/0034/0003. It was also partially supported by PortugueseFoundation for Science and Technology (FCT) inthe framework of projects PTDC/SAU-BEB/098391/2008 andPTDC/SAU-BEB/098392/2008
DS Minerva
RD 25 abr 2026