RT Book,_Section
T1 Computational Study on the effect of microhydration on amonium···phenol and methylammonium···phenol complexes
A1 Rodríguez Sanz, Ana Angustias
A1 Campo Cacharrón, Alba
A1 Cabaleiro Lago, Enrique Manuel
A1 Rodríguez Otero, Jesús
AB Interactions between cations and aromatic molecules can be often find on a large number of biomolecular systems, such as proteins and receptor-ligand complexes. In addition, its important role in biological processes such as molecular recognition, drug action, and protein folding has been revealed by extensive experimental and theoretical investigations. Most previous theoretical investigations of cation···p interactions, have been focused on their characteristics in the gas phase, with less attention to their behavior in aqueous environment. In this latter case, most of the work has been focused on the whole effect of water solution as a medium on the cation···p interactions. Hence, it is important studying the influence of individual water molecules on the interaction as the cation···p complex is sequentially hydrated. The ammonium···phenol and methylammonium···phenol cation···p complex was selected as a model system to explore how water molecules affect the cation···p interaction. To mimic the process of water molecules binding to a cation···p complex, water molecules were introduced into the complex one by one. The purpose of this study is studying the geometrical characteristic of cation···p complexes with different numbers of water molecules and to investigate how the binding of water molecules to an existing cation···p complex affects the cation···p interaction
PB MDPI
SN 3-906980-25-1
YR 2011
FD 2011
LK http://hdl.handle.net/10347/26904
UL http://hdl.handle.net/10347/26904
LA eng
NO Proceedings of the 15th International Electronic Conference on Synthetic Organic Chemistry, 1–30 November 2011, MDPI: Basel, Switzerland, doi:10.3390/ecsoc-15-00618
DS Minerva
RD 24 abr 2026