RT Journal Article
T1 Comparative clinicopathological study of the main anatomic locations of oral squamous cell carcinoma
A1 Amezaga Fernández, Iñaut
A1 Aguirre Urizar, José Manuel
A1 Suárez Peñaranda, José Manuel
A1 Chamorro Petronacci, Cintia Micaela
A1 Lafuente Ibáñez De Mendoza, Irene
A1 Marichalar Mendía, Xabier
A1 Somoza Martín, José Manuel
A1 Blanco Carrión, Andrés
A1 Antúnez López, José Ramón
A1 García García, Abel
K1 Anatomic location
K1 Cancer
K1 Floor of mouth
K1 Gingiva
K1 Lateral tongue
K1 Oral
K1 Oral squamous cell  carcinoma
AB ObjectiveTo analyze the clinicopathological and evolutionary profile of the main locations of oral squamous cell carcinoma (OSCC).Materials and MethodsThis is a retrospective study on 133 patients treated for OSCC. The group was composed of 48 women and 85 men, with a mean age 63.9 ± 12.73 years. Most cases involved the lingual border of tongue (63), followed by the gingiva (36) and the floor of mouth (34). A comparative analysis was performed using multinomial regression.ResultsThere were significant differences regarding age, sex, tobacco and alcohol consumption, liver pathology, oral potentially malignant disorders, and bone and perineural invasion. In multivariate regression, tobacco consumption, and bone invasion remained significant. There were no significant differences in relation to prognosis.ConclusionThe location of OSCC is an important factor in the clinicopathological assessment of this neoplasm. The main locations of OSCC show differential etiopathogenic and clinicopathological aspects. Tobacco consumption has a great relevance in the floor of mouth; nonetheless, it is less important in the tongue border and the gum, which suggests other pathogenic factors. It is necessary to consider the anatomical location of OSCC in preventive protocols, with the aim of reducing its high mortality
PB Wiley
SN 1354-523X
YR 2024
FD 2024-05-01
LK http://hdl.handle.net/10347/34918
UL http://hdl.handle.net/10347/34918
LA eng
NO Oral Diseases. 2024;00:1–9
NO This study received a research grant from the Jesús de Gangoiti Barrera Foundation. Authors' research is supported by the University of the Basque Country (UPV/EHU) (GUI21/042) and the University of Santiago de Compostela (USC) (GI 1319)
DS Minerva
RD 24 abr 2026