RT Dissertation/Thesis
T1 Role and predictive value of red blood cells in breast cancer metastasis
A1 Yáñez Gómez, Celso
K1 Breast Cancer (BC)
K1 metastasis
K1 bloodstream
K1 liquid biopsy
K1 red blood cells
AB Breast cancer is the most common cancer diagnosed in women around the world. Around 30% of the patients will eventually develop metastasis, which is responsible for 90 % of cancerrelated deaths. In order to find new biomarkers and therapy targets for these patients, it is important to study the metastatic process and the cells that take part in it. This thesis focused on the study of red blood cells, one of the most overlooked interplayer in cancer and metastasis. The results shown that RBCs from metastatic breast cancer patients were capable of interacting, and more importantly, modifying breast cancer cells, increasing their aggressiveness. Moreover, this thesis provided evidence of the RBCs potential to be used as predictive biomarkers of the presence of metastasis.
YR 2024
FD 2024
LK https://hdl.handle.net/10347/37670
UL https://hdl.handle.net/10347/37670
LA eng
DS Minerva
RD 24 abr 2026