RT Journal Article
T1 Optimal experimental design in the evaluation of food packaging compliance with safety regulations
A1 Mauricio Iglesias, Miguel
K1 Optimal Experimental Design
K1 Mass Transfer
K1 Parameter Estimation
K1 Uncertainty Analysis
K1 Food Technology
AB The determination of diffusivity of compounds that can be transferred from packaging into food products is a keystone to ensure consumer’s safety. However, no clear guidelines exist as how the diffusion experiment should be designed in order to maximise the accuracy of the estimated parameter.  With the perspective of optimal experimental design, a methodology to estimate the diffusivity of a migrating compound in a polymer is presented, both for global methods (that measure the overall concentration) and local methods (that measure the profile of concentration along the polymer thickness).  To demonstrate the methodology, real experimental data (transfer of Uvitex OB from linear low-density polyethylene) are used, and the OED based methodology is benchmarked against other heuristics. It is seen that, although the OED methodology outperforms the rest of methodologies when good initial guesses are available, its performance becomes deteriorated when gross over- or underestimations of the true value are made
PB Elsevier
SN 2405-8963
YR 2016
FD 2016
LK http://hdl.handle.net/10347/15032
UL http://hdl.handle.net/10347/15032
LA eng
NO Mauricio-Iglesias, M. (2016). Optimal experimental design in the evaluation of food packaging compliance with safety regulations. IFAC-PapersOnLine, vol. 49, no. 7, p. 1133-1138 [DOI 10.1016/j.ifacol.2016.07.355]
NO 11th IFAC Symposium on Dynamics and Control of Process SystemsIncluding Biosystems DYCOPS-CAB 2016 — Trondheim, Norway, 6—8 June 2016
NO The author would like to acknowledge the reviewers for very constructive comments that have contributed to improve this work. This work is funded by the People Program (Marie Curie Actions) of the European Union's Seventh Framework Programme FP7/2007-2013 under REA agreement 627475 (GREENCOST). The author belongs to the Galician Competitive Research Group GRC 2013-032, programme cofunded by FEDER
DS Minerva
RD 24 abr 2026