RT Journal Article
T1 Rationale and methods of the multicenter randomised trial of a heart failure management programme among geriatric patients (HF-Geriatrics)
A1 Rodríguez Pascual, Carlos
A1 Paredes Galán, Emilio
A1 González Guerrero, José Luís
A1 Menéndez Colino, Rocío
A1 Abizanda Soler, Pedro
A1 Hornillos Calvo, Mercedes
A1 Solano Jaurieta, Juan José
A1 Manzarbeitia Arambarri, Jorge
A1 Ribera Casado, Jose Manuel
A1 Rodríguez Artalejo, Fernando
K1 Heart Failure
K1 Chronic Obstructive Pulmonary Disease
K1 Case Manager
K1 Disease Management Programme
K1 Hospital Readmission
AB Background: Disease management programmes (DMPs) have been shown to reduce hospital readmissions and mortality in adults with heart failure (HF), but their effectiveness in elderly patients or in those with major comorbidity is unknown. The Multicenter Randomised Trial of a Heart Failure Management Programme among Geriatric Patients (HF-Geriatrics) assesses the effectiveness of a DMP in elderly patients with HF and major comorbidity.Methods/Design: Clinical trial in 700 patients aged ≥ 75 years admitted with a primary diagnosis of HF in the acute care unit of eight geriatric services in Spain. Each patient should meet at least one of the following comorbidty criteria: Charlson index ≥ 3, dependence in ≥ 2 activities of daily living, treatment with ≥ 5 drugs, active treatment for ≥ 3 diseases, recent emergency hospitalization, severe visual or hearing loss, cognitive impairment, Parkinson's disease, diabetes mellitus, chronic obstructive pulmonary disease (COPD), anaemia, or constitutional syndrome. Half of the patients will be randomly assigned to a 1-year DMP led by a case manager and the other half to usual care. The DMP consists of an educational programme for patients and caregivers on the management of HF, COPD (knowledge of the disease, smoking cessation, immunizations, use of inhaled medication, recognition of exacerbations), diabetes (knowledge of the disease, symptoms of hyperglycaemia and hypoglycaemia, self-adjustment of insulin, foot care) and depression (knowledge of the disease, diagnosis and treatment). It also includes close monitoring of the symptoms of decompensation and optimisation of treatment compliance. The main outcome variables are quality of life, hospital readmissions, and overall mortality during a 12-month follow-up.Discussion: The physiological changes, lower life expectancy, comorbidity and low health literacy associated with aging may influence the effectiveness of DMPs in HF. The HF-Geriatrics study will provide direct evidence on the effect of a DMP in elderly patients with HF and high comorbidty, and will reduce the need to extrapolate the results of clinical trials in adults to elderly patients
PB BMC
YR 2011
FD 2011
LK http://hdl.handle.net/10347/23079
UL http://hdl.handle.net/10347/23079
LA eng
NO Pascual, C.R., Galán, E.P., Guerrero, J.L.G. et al. Rationale and methods of the multicenter randomised trial of a heart failure management programme among geriatric patients (HF-Geriatrics). BMC Public Health 11, 627 (2011). https://doi.org/10.1186/1471-2458-11-627
NO Study partially funded by the Fondo de Investigación Sanitaria, Instituto de Salud Carlos III (PI-081820), the Fondo Europeo de Desarrollo Regional (FEDER) "una manera de hacer Europa" and by the INCITE programme of the Xunta de Galicia (08CSA063905PR)
DS Minerva
RD 24 abr 2026