RT Journal Article
T1 Yessotoxin, a promising therapeutic tool
A1 Alfonso Rancaño, María Amparo
A1 Rodríguez Vieytes, Mercedes
A1 Botana López, Luis Miguel
K1 Yessotoxin (YTX)
K1 Apoptosis
K1 Autophagy
K1 Cellular death
K1 Signal transduction
K1 Cytoskeleton
K1 Immune system
K1 Alzheimer
K1 Glucose metabolism
AB Yessotoxin (YTX) is a polyether compound produced by dinoflagellates and accumulated in filter feeding shellfish. No records about human intoxications induced by this compound have been published, however it is considered a toxin. Modifications in second messenger levels, protein levels, immune cells, cytoskeleton or activation of different cellular death types have been published as consequence of YTX exposure. This review summarizes the main intracellular pathways modulated by YTX and their pharmacological and therapeutic implications
PB MDPI
YR 2016
FD 2016-01-28
LK http://hdl.handle.net/10347/15901
UL http://hdl.handle.net/10347/15901
LA eng
NO Alfonso, A.; Vieytes, M.R.; Botana, L.M. Yessotoxin, a Promising Therapeutic Tool. Mar. Drugs 2016, 14, 30
NO The research leading to these results has received funding from the following FEDERcofunded grants. From CDTI and Technological Funds, supported by Ministerio de Economía y Competitividad, AGL2012-40185-CO2-01, AGL2014-58210-R; Consellería de Cultura, Educación e Ordenación Universitaria, GRC2013-016; CDTI under ISIP Programme, Spain, IDI-20130304 APTAFOOD; and the European Union’s Seventh Framework Programme managed by REA—Research Executive Agency (FP7/2007–2013) under grant agreement 312184 PHARMASEA
DS Minerva
RD 1 may 2026