RT Journal Article
T1 Genetic continuity in the Franco-Cantabrian Region: new clues from autochthonous mitogenomes
A1 Gómez Carballa, Alberto
A1 Olivieri, Anna
A1 Behar, Doron M.
A1 Achilli, Alessandro
A1 Torroni, Antonio
A1 Salas Ellacuriaga, Antonio
AB Background: The  Late  Glacial  Maximum  (LGM), ∼20  thousand  years  ago  (kya),  is  thought  to  have  forced  the  peopleinhabiting  vast  areas  of  northern  and  central  Europe  to  retreat  to  southern  regions  characterized  by  milder  climaticconditions. Archaeological records indicate that Franco-Cantabria might have been the major source for the re-peopling ofEurope at the beginning of the Holocene (11.5  kya). However, genetic evidence is still scarce and has been the focus of anintense  debate.Methods/Principal Findings:Based on a survey of more than 345,000 partial control region sequences and the analysis of53 mitochondrial DNA (mtDNA) genomes, we identified an mtDNA lineage, HV4a1a, which most likely arose in the Franco-Cantabrian  area  about  5.4  kya  and  remained  confined  to  northern  Iberia.Conclusions/Significance:The  HV4a1a  lineage  and  several  of  its  younger  branches  reveal  for  the  first  time  geneticcontinuity in this region and long-term episodes of isolation. This, in turn, could at least in part explain the unique linguisticand  cultural  features  of  the  Basque  region.
PB PLOS
YR 2012
FD 2012
LK http://hdl.handle.net/10347/21796
UL http://hdl.handle.net/10347/21796
LA eng
NO Gómez-Carballa A, Olivieri A, Behar DM, Achilli A, Torroni A, Salas A (2012) Genetic Continuity in the Franco-Cantabrian Region: New Clues from Autochthonous Mitogenomes. PLoS ONE 7(3): e32851. https://doi.org/10.1371/journal.pone.0032851
NO This  research  study  received  support  from  the  Fundación  de  Investigación Médica  Mutua  Madrileña  (to  AS), the Ministerio de Ciencia e Innovación(SAF2008-02971) (to AS), the Progetti Ricerca Interesse Nazionale 2009 (Italian Ministry of the University) (to AA and AT), the FIRB-Futuro in Ricerca (Italian Ministry of the University) (to AA and AO), the Fondazione Alma Mater Ticinensis (to AT)
DS Minerva
RD 23 abr 2026