RT Journal Article
T1 Axially Chiral Triazoloisoquinolin-3-ylidene Ligands in Gold(I)-Catalyzed Asymmetric Intermolecular (4 + 2) Cycloadditions of Allenamides and Dienes
A1 Francos Arias, Javier
A1 Grande-Carmona, Francisca
A1 Faustino, Hélio
A1 Iglesias Sigüenza, Francisco Javier
A1 Díez Martín, Elena
A1 Alonso García, Isaac
A1 Fernández Fernández, Rosario Fátima
A1 Lassaletta, José M.
A1 López García, Fernando
A1 Mascareñas Cid, José Luis
AB The first highly enantioselective intermolecular (4 + 2) cycloaddition between allenes and dienes is reported. The reaction provides good yields of optically active cyclohexenes featuring diverse substitution patterns and up to three stereocenters. Key to the success of the process is the use of newly designed axially chiral N-heterocyclic carbene–gold catalysts
PB American Chemical Society
SN 0002-7863
YR 2012
FD 2012
LK http://hdl.handle.net/10347/18480
UL http://hdl.handle.net/10347/18480
LA eng
NO Francos, J., Grande-Carmona, F., Faustino, H., Iglesias-Sigüenza, J., Díez, E., Alonso, I., Fernández, R., Lassaletta, J.M., López, F. and Mascareñas, J.L. (2012). Axially Chiral Triazoloisoquinolin-3-ylidene Ligands in Gold(I)-Catalyzed Asymmetric Intermolecular (4 + 2) Cycloadditions of Allenamides and Dienes. J. Am. Chem. Soc., 134, 35, 14322-14325. doi: 10.1021/ja3065446
NO This work was supported by the Spanish MINECO (SAF2010-20822-C02, CTQ2010-15297, CTQ2010-14974, and Consolider Ingenio 2010 CSD2007-00006), the ERDF funds, the Xunta de Galicia (INCITE09209084PR, GRC2010/12), and the Junta de Andalucía (2008/FQM-3833 and 2009/FQM-4537, predoctoral fellowship to F.G.-C). H.F. acknowledges the Fundação para a Ciência e Tecnologia (FCT, Portugal) and POPH/FSE for a Ph.D. grant (Grant SFRH/BD/60214/2009)
DS Minerva
RD 24 abr 2026