RT Journal Article T1 Comparing distance-decay parameters: A novel test under pairwise dependence A1 Martín Devasa, Ramiro María A1 Martínez Santalla, Sara A1 Gómez Rodríguez, Carola A1 Crujeiras Casais, Rosa María A1 Baselga Fraga, Andrés K1 β-Diversity K1 Distance-decay K1 Iberian vertebrates K1 Pairwise dependence K1 Parameter comparison K1 Site-block resampling AB Foal meat is considered a healthy alternative to other meat sources and more environmentally sustainable. However, its quality is highly variable and there is lack of knowledge about the molecular mechanisms underlying its determination. Genotype and diet play a relevant role as the main factors that can allow a control of the final quality and the use of high-throughput analytical methods such as proteomics is a way to achieve this lofty goal. This research aimed to study-two breeds (Burguete and Jaca Navarra) supplemented with two different finishing diets: conventional concentrate and straw (C) vs silage and organic feed (S). The proteomic approach built a library of 294 proteins that were subjected to several statistical and bioinformatic analyses. Burguete breed finished with concentrate produced higher meat quality in terms of tenderness, intramuscular fat and color lightness mainly due to the high abundance of energy metabolic proteins. Tenderness was correlated to myofibrillar proteins (ACTA1, MYBPH, MYL1 and TNNC1) and energy metabolic proteins (ALDOA, CKM, TPI1 and PGMA2). Regarding color, the main pathways were energy metabolism, involving several glycolytic enzymes (ALDOA, PKM, PFKM and CKM). Oxidative stress and response to stress proteins (HSPA1A, SOD2 and PRDX2) were further involved in color variation. Moreover, we revealed that several proteins were related to the intramuscular fat accordingly to the breed. This study proposed several candidate protein biomarkers for foal meat quality that are worthy to evaluate in the future PB Elsevier YR 2022 FD 2022 LK http://hdl.handle.net/10347/29488 UL http://hdl.handle.net/10347/29488 LA eng NO Ecological Informatics 72 (2022) 101894 NO Daniel Franco and José M. Lorenzo belong to the competitive reference research group, FunMeat (Axencia Galega de Innovación, GAININ607A2019/01) and Daniel Franco and Jose M. Lorenzo are members of the HealthyMeat network, funded by CYTED (Ref.119RT0568). Thanks go to the Universidad Pública de Navarra for granting Aurora Cittadini with a predoctoral scholarship (Resolution 787/2019) DS Minerva RD 24 abr 2026