RT Journal Article T1 Epidemiology of Aichi virus in fecal samples from outpatients with acute gastroenteritis in Northwestern Spain A1 Rivadulla Veira, Enrique A1 Varela, Miguel F. A1 López Romalde, Jesús K1 Aichi virus K1 Genotyping K1 Epidemiology K1 Gastroenteritis AB BackgroundIn recent years, Aichi virus (AiV) has been involved in acute viral gastroenteritis outbreaks. However, the common pathogenesis of AiV releases more in subclinical infections underestimating the impact of AiV in human health.ObjectivesThe present study describes the presence and genetic diversity of AiV in patients with gastroenteritis in Northwestern Spain. Study design: A total of 2667 stool samples, obtained between July 2010 and June 2011, from diarrheic outpatients were studied for detection and molecular characterization of AiV using PCR techniques followed by sequencing and phylogenetic analyses.ResultsThe virus was detected in 124 (5.0%) of the samples among all age groups. Coinfections were also detected, from the 124 positive samples, 72 (58.1%) were positive only for AiV, whereas mixed contaminations with Norovirus genogroup I or genogroup II, Sapovirus, or other enteric pathogens were detected in 52 (41.9%) samples. A total of 70 positive samples could be genotyped, being characterized as genotype A (58.6%) or B (41.4%). AiV was detected from August to April, being the highest number of AiV positive samples detected during autumn and winter seasons.ConclusionsThis survey remarks the importance of emerging enteric viruses in patients who require medical assistance, and offers more information about the real importance of AiV as gastroenteritis agent. PB Elsevier SN 1386-6532 YR 2019 FD 2019-09-01 LK https://hdl.handle.net/10347/38864 UL https://hdl.handle.net/10347/38864 LA eng NO Enrique Rivadulla, Miguel F. Varela, Jesús L. Romalde, Epidemiology of Aichi virus in fecal samples from outpatients with acute gastroenteritis in Northwestern Spain, Journal of Clinical Virology, Volume 118, 2019, Pages 14-19, ISSN 1386-6532, https://doi.org/10.1016/j.jcv.2019.07.011. NO Grant 2014-PG110 (Xunta de Galicia) DS Minerva RD 28 abr 2026