RT Journal Article
T1 Impact of Acute Lymphoblastic Leukaemia Treatment on the Nutritional Status of Paediatric Patients: A Systematic Review
A1 Picáns Leis, Rosaura
A1 Nieto, Fátima
A1 Romero-Agrelo, Anabel
A1 Izquierdo-López, Isabel
A1 Rivas-Rodríguez, Lucía
A1 Vázquez Cobela, Rocío
A1 Leis Trabazo, María Rosaura
K1 Systematic review
K1 Leukaemia
K1 Children
K1 Treatment
K1 Nutritional status
K1 Nutrition assessment
AB Abstract: Introduction: Acute lymphoblastic leukaemia (ALL) is the most prevalent cancer in childhood and is one of the leading causes of death annually. Antineoplastic treatments are associated with a high risk of malnutrition, which is important for continuous growth and development.Objective: This systematic review aimed to evaluate the effect of these treatments on the nutritional status of paediatric patients with ALL. Data were collected from the PubMed, Scopus, and Web of Science databases following the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) method. All the studies in which nutritional status was assessed in human beings diagnosed with ALL up to 18 years and published in English or Spanish between January 1900 and December 2023 were included. Results: A total of 18 articles and 1692 participants were analysed in this review. Article quality was evaluated using the ROBINS-I tool. This systematic review has been registered on PROSPERO (CRD42024505111). ALL treatment has a negative impact on the nutritional status of these patients and played an important role in their growth and global development. ALL treatments can modify hunger perception and the palatability of food. Conclusions: Nutritional status is important for patient prognosis and survival. Nutritional evaluation, a specific nutritional assessment, and follow-up should be recommended for these patients to decrease the nutritional impact on global health. More homogeneous studies must be conducted to reach robust conclusions regarding the best type of nutritional intervention for these patients.
PB MPDI
SN 2072-6643
YR 2024
FD 2024-11-28
LK https://hdl.handle.net/10347/45243
UL https://hdl.handle.net/10347/45243
LA eng
NO Picáns-Leis, R.; Nieto, F.; Romero-Agrelo, A.; Izquierdo-López, I.; Rivas-Rodríguez, L.; Vázquez- Cobela, R.; Leis, R. Impact of Acute Lymphoblastic Leukaemia Treatment on the Nutritional Status of Paediatric Patients: A Systematic Review. Nutrients 2024, 16, 4119. https:// doi.org/10.3390/nu16234119
NO This study received external funding from IDI-20190982.
DS Minerva
RD 24 abr 2026