RT Journal Article
T1 Hiperactivation of right inferior frontal cortex in young binge drinkers during response inhibition: A follow-up study
A1 López Caneda, Eduardo Guillermo
A1 Cadaveira Mahía, Fernando
A1 Crego Barreiro, Manuel Alberto
A1 Gómez Suárez, Ana Fátima
A1 Corral Varela, María Montserrat
A1 Parada Iglesias, María
A1 Caamaño Isorna, Francisco
A1 Rodríguez Holguín, Socorro
K1 Binge drinking
K1 eLORETA
K1 Event-related potentials
K1 Inhibitory control
K1 NoGo-P3
K1 Prefrontal cortex
K1 Consumo intensivo de alcohol
K1 Potenciales evocados
K1 Córtex prefrontal
AB Aims: The objective of this study was to examine brain activity, with particular attention to prefrontal function, during response execution and inhibition in youths who have engaged in binge drinking (BD) for at least 2 years. Design: Event‐related potentials (ERPs) were recorded twice within 3 years, during performance of a Go/NoGo task. Setting: The study was part of a longitudinal study of the neurocognitive effects of BD. Participants: A total of 48 undergraduate students, 25 controls (14 females) and 23 binge drinkers (10 females), with no personal or family history of alcoholism or psychopathological disorders. Measurements: The Go‐P3 and NoGo‐P3 components of the ERPs were examined by principal component analysis and exact low‐resolution tomography analysis (eLORETA). Findings: Binge drinkers showed larger Go‐P3 amplitudes than controls in the first and second evaluations (P = 0.019). They also showed larger NoGo‐P3 amplitude in the second evaluation (P = 0.002). eLORETA analyses in the second evaluation revealed significantly greater activation of the right inferior frontal cortex (rIFC) in binge drinkers than in controls during successful inhibition (P < 0.05). Conclusions: Young binge drinkers appear to show abnormal brain activity as measured by event‐related potentials during response execution and inhibition which may represent a neural antecedent of difficulties in impulse control
PB Wiley
SN 0965-2140
YR 2012
FD 2012
LK http://hdl.handle.net/10347/16831
UL http://hdl.handle.net/10347/16831
LA eng
NO López-Caneda E; Cadaveira F; Crego A; Gómez-Suárez AF; Corral M; Parada M; Caamaño F; Rodríguez Holguín S (2012). Hiperactivation of right inferior frontal cortex in young binge drinkers during response inhibition: a follow-up study, Addiction, 107, 1796-1808. Doi:10.1111/j.1360-0443.2012.03908.x
NO This is the peer reviewed version of the following article: López-Caneda E; Cadaveira F; Crego A; Gómez-Suárez AF; Corral M; Parada M; Caamaño F; Rodríguez Holguín S (2012). Hiperactivation of right inferior frontal cortex in young binge drinkers during response inhibition: a follow-up study, Addiction, 107, 1796-1808, which has been published in final form at https://doi.org/10.1111/j.1360-0443.2012.03908.x. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions
NO The study was supported by a grant from the Consellería de Industria e Inovación Sectorial de la Xunta de Galicia (INCITE08PXIB211015PR), two grants from the Ministerio de Ciencia e Innovación of Spain (EDU2008‐03400; PSI2011‐22575) and through the FPU programme (AP2008‐03433) of the Ministerio de Educación of Spain
DS Minerva
RD 24 abr 2026