RT Journal Article
T1 Analysis of naturally occurring steroid hormones in infant formulas by HPLC-MS/MS and contribution to dietary intake
A1 Barreiro Tomé, Rocío
A1 Regal López, Patricia
A1 Díaz Bao, Mónica
A1 Fente Sampayo, Cristina Asunción
A1 Cepeda Sáez, Alberto
K1 Infant formulas
K1 Steroid hormone
K1 Estrogen
K1 Progestogen
K1 Androgen
K1 Breast milk
K1 Bovine milk
K1 Daily intake
K1 LC-MS/MS
AB Milk is a natural fluid and as such contains small amounts of naturally occurring steroids. Human milk is recommended as the optimal source of nutrients for infants and young children, and it has been associated to several short- and long-term benefits. For this reason, its composition is used as a reference for designing infant formulas. However, the available information on the hormonal levels of these dairy products is scarce, and it is usually limited to estradiol and estrone. In the present study, six natural sex hormones (pregnenolone, progesterone, estrone, dehydroepiandrosterone, testosterone and androstenedione) have been extracted from sixteen milk-based infant formulas and analyzed with liquid chromatography tandem mass spectrometry (HPLC-MS/MS). The purpose of this research was to quantify natural steroid hormones in various infant formulas, to provide food and nutrition practitioners with information to estimate intakes in children. In addition, data found in the literature was used for comparison. The findings suggest that there are certain similarities between bovine milk and dairy products for infants. Furthermore, the detected levels were in general lower than those observed in human milk and/or colostrum. The reported results represent a valuable addition to the current knowledge on natural hormone content of infant foods
PB MDPI
YR 2015
FD 2015
LK http://hdl.handle.net/10347/21741
UL http://hdl.handle.net/10347/21741
LA eng
NO Barreiro, R.; Regal, P.; Díaz-Bao, M.; Fente, C.A.; Cepeda, A. Analysis of Naturally Occurring Steroid Hormones in Infant Formulas by HPLC-MS/MS and Contribution to Dietary Intake. Foods 2015, 4, 605-621
DS Minerva
RD 28 abr 2026