RT Dissertation/Thesis
T1 New synthetic routes towards 1,4- dienylboronates via catalytic alkyne allylboration reactions
A1 Rivera Chao, Eva
K1 Multicomponent reactions
K1 Catalysis
K1 Boron
K1 Copper
K1 Allylboration
K1 Skipped dienes
AB In this Ph.D. thesis, the synthesis of 1,4-dienyl boronates is explored using transition metal-catalyzed methodologies. In chapter I an introduction about the most important features of organoboron compounds and the most common methods to synthetize them is reported. Chapter II describes the synthesis of linear borylated 1,4-dienes through a synergistic Cu/Pd catalyzed stereo- and regioselective allylboration of alkynes. In chapter III, we explore the synthesis of multifunctional branched borylated 1,4-dienes by means of a copper-catalyzed stereo- and regioselective allylboration of alkynes. Then, we report the use of  these 1,4-dienes for the synthesis of a new type of organoboron compounds, borylated dendralenes. In chapter IV, an enantioselective version of the allylboration of alkynes reported in chapter III with a chiral copper catalyst is disclosed. Finally, chapter V details the discovery of a novel transformation that entails á la carte multifunctionalization of borylated dendralenes to access to highly substituted 1,3-dienes.
YR 2022
FD 2022
LK http://hdl.handle.net/10347/27566
UL http://hdl.handle.net/10347/27566
LA eng
DS Minerva
RD 29 abr 2026