RT Journal Article
T1 Aniserp: a new serpin from the parasite Anisakis simplex
A1 Valdivieso, Elizabeth
A1 Perteguer, María Jesús
A1 Hurtado, Carolina
A1 Campioli, Pamela
A1 Rodríguez, Esperanza
A1 Saborido, Ana
A1 Martínez Sernández, Victoria
A1 Gómez Puertas, Paulino
A1 Martínez Ubeira, Florencio César
A1 Gárate, Teresa
K1 Serpin
K1 Proteinase
K1 Anisakis
K1 Trypsin
K1 Thrombin
K1 Cathepsin L
K1 Anticoagulant properties
K1 Modelling analysis
K1 Heparin
AB Serine proteinase inhibitors (serpins) finely regulate serine proteinase activity via a suicide substrate-like inhibitory mechanism. In parasitic nematodes, some serpins interact with host physiological processes; however, little is known about these essential molecules in Anisakis. This article reports the gene sequencing, cloning, expression and preliminary biochemical and bioinformatically-based structural characterization of a new Anisakis serpin (ANISERP)
PB BioMed Central
SN 1756-3305
YR 2015
FD 2015
LK http://hdl.handle.net/10347/21698
UL http://hdl.handle.net/10347/21698
LA eng
NO Valdivieso, E., Perteguer, M.J., Hurtado, C. et al. ANISERP: a new serpin from the parasite Anisakis simplex . Parasites Vectors 8, 399 (2015). https://doi.org/10.1186/s13071-015-1006-z
NO This work was funded by the Spanish Ministry of Science and Innovation (SAF2002-04057-CO2-01) and the Instituto de Salud Carlos III (ISCIII) as part of project MPY 1404/09, and ISCIII-AESI project MPY 1279/15. Carolina Hurtado and Pamela Campioli were supported by grants from the ISCIII (Fondo de InvestigacionesSanitarias), through VI NP of I + D + I (2008–2011), ISCIII- General Sub-Direction of Networks and Centers for Collaborative Research (RETIC-RICET, RD06/0021/0019, RD12/0018/011). Victoria Martínez Sernández holds a predoctoral fellowship from the Spanish Ministerio de Educación, Cultura y Deporte (Programa de Formación del Profesorado Universitario)
DS Minerva
RD 23 abr 2026