RT Journal Article
T1 Comparison of UV, chlorination, UV-hydrogen peroxide and UV-chlorine processes for tramadol removal: Kinetics study and transformation products identification
A1 Cobo Golpe, Miguel
A1 Fernández Fernández, Victoria
A1 Arias, T.
A1 Ramil Criado, María
A1 Cela Torrijos, Rafael
A1 Rodríguez Pereiro, Isaac
K1 Tramadol
K1 Oxidative processes
K1 Liquid chromatography mass spectrometry
K1 Removal efficiency
K1 Transformation products
AB Tramadol (TRA) is a poorly biodegradable pharmaceutical, ubiquitously distributed in the aquatic environment. Herein, we present a thorough comparison of two conventional (UV and chlorination) and two advanced oxidative processes (UV-H2O2 and UV-chlorine), in terms of TRA removal efficiency and transformation products (TPs) formation. The performance of these processes was evaluated in different complexity water samples, previously adjusted at neutral pH. Using 1 mg L−1 as initial concentration of oxidant, UV-chlorine was the most effective process followed by UV-H2O2, direct photolysis and chlorination. The efficiency of the investigated treatments decreased for surface and wastewater samples compared to model solutions. Despite this limitation, the UV-chlorine treatment removed more than 70% of TRA measured in wastewater samples after 5 min of UV irradiation, in presence of 10 mg L−1 of chlorine. UV-chlorine involved additional degradation routes to those described for the rest of treatments, including the formation of tramadol-N-oxide, several chlorinated derivatives, and the volatile species chloroform, 1,1-dichloroacetone and anisole. Some of these specific TPs might pose a similar toxicity to that associated to the parent compound; however, their maximum formation yields remained below 2.5%, decreasing steady for reaction times longer than 5 min
PB Elsevier
YR 2022
FD 2022
LK http://hdl.handle.net/10347/29051
UL http://hdl.handle.net/10347/29051
LA eng
NO Journal of Environmental Chemical Engineering  10 (2022) 107854
NO This study was supported through grants PGC2018-094613-B-I00 and ED431C 2021/06, funded by Spanish Government (Ministry of Science, Innovation and Universities) and Xunta de Galicia, respectively. Both projects are co-funded by the EU FEDER program. M.C.G. thanks a FPI fellowship to the Ministry of Science and Education (Spain)
DS Minerva
RD 26 abr 2026