RT Journal Article
T1 The Paleo-Indian Entry into South America According to Mitogenomes
A1 Brandini, Stefania
A1 Bergamaschi, Paola
A1 Cerna, Marco Fernando
A1 Gandini, Francesca
A1 Bastaroli, Francesca
A1 Bertolini, Emilie
A1 Cereda, Cristina
A1 Ferretti, Luca
A1 Gómez Carballa, Alberto
A1 Battaglia, Vicenza
A1 Salas Ellacuriaga, Antonio
A1 Semino, Ornella
A1 Achilli, Alessandro
A1 Olivieri, Anna
A1 Torroni, Antonio
K1 Native Americans
K1 Mitochondrial DNA
K1 Mitochondrial genomes
K1 Haplogroups
K1 First peopling of South America
K1 Ecuador
K1 Peru
AB Recent and compelling archaeological evidence attests to human presence ∼14.5 ka at multiple sites in South America and a very early exploitation of extreme high-altitude Andean environments. Considering that, according to genetic evidence, human entry into North America from Beringia most likely occurred ∼16 ka, these archeological findings would imply an extremely rapid spread along the double continent. To shed light on this issue from a genetic perspective, we first completely sequenced 217 novel modern mitogenomes of Native American ancestry from the northwestern area of South America (Ecuador and Peru); we then evaluated them phylogenetically together with other available mitogenomes (430 samples, both modern and ancient) from the same geographic area and, finally, with all closely related mitogenomes from the entire double continent. We detected a large number (N = 48) of novel subhaplogroups, often branching into further subclades, belonging to two classes: those that arose in South America early after its peopling and those that instead originated in North or Central America and reached South America with the first settlers. Coalescence age estimates for these subhaplogroups provide time boundaries indicating that early Paleo-Indians probably moved from North America to the area corresponding to modern Ecuador and Peru over the short time frame of ∼1.5 ka comprised between 16.0 and 14.6 ka
PB Oxford University Press
SN 0737-4038
YR 2018
FD 2018
LK http://hdl.handle.net/10347/24291
UL http://hdl.handle.net/10347/24291
LA eng
NO Molecular Biology and Evolution, Volume 35, Issue 2, February 2018, Pages 299–311, https://doi.org/10.1093/molbev/msx267
NO This study received support from the University of Pavia strategic theme “Towards a governance model for international migration: An interdisciplinary and diachronic perspective” (MIGRAT-IN-G) (to A.O., A.A., O.S., and A.T.), and the Italian Ministry of Education, University and Research: Progetti Futuro in Ricerca 2012 (RBFR126B8I) (to A.O. and A.A.) and Progetti Ricerca Interesse Nazionale 2012 (to A.A, O.S., and A.T.)
DS Minerva
RD 25 abr 2026