RT Journal Article
T1 Minimally invasive non-surgical periodontal therapy of intrabony defects: A prospective multi-centre cohort study
A1 Mehta, Jaimini
A1 Montevecchi, Marco
A1 García Sánchez, Rubén
A1 Onabolu, Olanrewaju
A1 Liñares, Antonio
A1 Eriksson, Fernando
A1 Ghezzi, Carlo
A1 Donghi, Camilla
A1 Ming-Chieh Lu, Emily
A1 Nibali, Luigi
K1 Debridement
K1 Intrabony defects
K1 Minimally invasive non-surgical therapy (MINST)
K1 Periodontitis
AB AimTo assess the potential benefits of minimally invasive non-surgical therapy (MINST) in teeth with intrabony defects and to explore factors associated with the outcomes.Materials and MethodsA multi-centre trial was conducted in 100 intrabony defects in periodontitis patients in private practice. Steps 1 and 2 periodontal therapy including MINST were provided. Clinical and radiographic data were analysed at baseline and 12 months after treatment, with the primary aim being change in radiographic defect depth at 12 months.ResultsEighty-four patients completed the 12-month follow up. The mean total radiographic defect depth reduced by 1.42 mm and the defect angle increased by 3° (both p < .05). Statistically significant improvements in probing pocket depth (PPD) and clinical attachment level (CAL) were seen at 12 months compared to baseline (p < .001). Fifty-six defects (66.7%) achieved pocket closure (PPD ≤ 4 mm) and 49 defects (58.3%) achieved the composite outcome (PPD ≤ 4 mm and CAL gain ≥3 mm). Deeper and narrower angled defects were positively correlated with radiographic and clinical improvements, respectively.ConclusionsImprovements in clinical and radiographic outcomes were seen after MINST. This study highlights the generalizability and wide applicability of this approach, further supporting its effectiveness in the treatment of intrabony defects. Clinical trial registration: NCT03741374. https://clinicaltrials.gov/study/NCT03741374?cond=minimally%20invasive%20non%20surgical%20therapy&locStr=UK&country=United%
PB Wiley
SN 0303-6979
YR 2024
FD 2024-05-06
LK https://hdl.handle.net/10347/41331
UL https://hdl.handle.net/10347/41331
LA eng
NO Mehta, J., Montevecchi, M.,Garcia-Sanchez, R., Onabolu, O., Liñares, A., Eriksson, F.,Ghezzi, C., Donghi, C., Lu, E. M.-C., & Nibali, L. (2024).Minimally invasive non-surgical periodontal therapy ofintrabony defects: A prospective multi-centre cohort study.Journal of Clinical Periodontology, 51(7), 905–914. https://doi.org/10.1111/jcpe.13984914 MEHTA ET AL .
DS Minerva
RD 28 abr 2026