RT Journal Article
T1 Whole genome sequencing of turbot (Scophthalmus maximus; Pleuronectiformes): A fish adapted to demersal life
A1 Figueras, Antonio
A1 Robledo Sánchez, Diego
A1 Corvelo, André
A1 Hermida Prieto, Miguel
A1 Pereiro, Patricia
A1 Rubiolo Gaytán, Juan Andrés
A1 Gómez Garrido, Jèssica
A1 Carreté, Laia
A1 Bello Paderne, Xabier
A1 Gut, Marta
A1 Marcet-Houben, Marina
A1 Forn-Cuní, Gabriel
A1 Galán, Beatriz
A1 García López, José Luis
A1 Abal Fabeiro, José Luis
A1 Gómez Pardo, María Belén
A1 Taboada Penoucos, Xoana
A1 Fernández López, José Carlos
A1 Vlasova, Anna
A1 Hermoso Pulido, Toni
A1 Guigo, Roderic
A1 Álvarez Dios, José Antonio
A1 Gómez Tato, Antonio
A1 Viñas Díaz, Ana María
A1 Maside Rodríguez, Xulio Manuel
A1 Gabaldón, Toni
A1 Novoa, Beatriz
A1 Bouza Fernández, María Carmen
A1 Alioto, Tyler
A1 Martínez Portela, Paulino
K1 Turbot
K1 Genome sequencing
K1 Genetic map
K1 Genome evolution
K1 Productive traits
AB The turbot is a flatfish (Pleuronectiformes) with increasing commercial value, which has prompted active genomic research aimed at more efficient selection. Here we present the sequence and annotation of the turbot genome, which represents a milestone for both boosting breeding programmes and ascertaining the origin and diversification of flatfish. We compare the turbot genome with model fish genomes to investigate teleost chromosome evolution. We observe a conserved macrosyntenic pattern within Percomorpha and identify large syntenic blocks within the turbot genome related to the teleost genome duplication. We identify gene family expansions and positive selection of genes associated with vision and metabolism of membrane lipids, which suggests adaptation to demersal lifestyle and to cold temperatures, respectively. Our data indicate a quick evolution and diversification of flatfish to adapt to benthic life and provide clues for understanding their controversial origin. Moreover, we investigate the genomic architecture of growth, sex determination and disease resistance, key traits for understanding local adaptation and boosting turbot production, by mapping candidate genes and previously reported quantitative trait loci. The genomic architecture of these productive traits has allowed the identification of candidate genes and enriched pathways that may represent useful information for future marker-assisted selection in turbot
PB Oxford University Press
YR 2016
FD 2016
LK http://hdl.handle.net/10347/26149
UL http://hdl.handle.net/10347/26149
LA eng
NO DNA Research, Volume 23, Issue 3, June 2016, Pages 181–192, https://doi.org/10.1093/dnares/dsw007
NO This work was funded by the Spanish Government: projects Consolider Ingenio: Aquagenomics (CSD2007-00002) and Metagenoma de la Península Ibérica (CSD2007-00005), Ministerio de Economía y Competitividad and European Regional Development Funds (AGL2012-35904), and Ministerio de Economía y Competitividad (AGL2014-51773 and AGL2014-57065-R); and Local Government Xunta de Galicia (GRC2014/010). P.P. and D.R. gratefully acknowledge the Spanish Ministerio de Educación for their FPU fellowships (AP2010-2408, AP2012-0254)
DS Minerva
RD 24 abr 2026