RT Journal Article
T1 Ethyl 1-O-tert-butyldimethylsilyl-2,3-Oisopropylidene-5-[(20S)-tetrahydropyran2-yloxy]-D-glycero-a-D-manno-heptofuronate
A1 González Soengas, Raquel María
A1 Valencia Matarranz, Laura
A1 Estévez Cabanas, Juan Carlos
A1 Estévez Cabanas, Ramón José
K1 Single-crystal X-ray study
K1 R factor = 0.067
K1 wR factor = 0.264
K1 Data-to-parameter ratio = 18.1.
K1 Mean  (C–C) = 0.012 A˚
K1 T = 293 K
AB The title compound {systematic name: (2S,3R)-ethyl 3-[(3aS,4R,6S,6aS)-6-tert-butyldimethylsilyloxy-2,2-dimethylperhydrofuro[3,4-d][1,3]dioxol-4-yl]-2-nitro-3-[(S)-tetrahydro-2H-pyran-2-yloxy]propanoate}, C23H41NO10Si, is theproduct of the Henry reaction of 1-O-tert-butyldimethylsilyl2,3-O-isopropylidene--d-lyxo-pentadialdo-1,4-furanose withethyl nitroacetate and the subsequent protection of its C-5hydroxy group as tetrahydropyranyl, in order to avoid theretro-Henry reaction. The tetrahydropyranyl group adopts achair conformation. The absolute configuration, assumedfrom the synthesis, was confirmed from the diffraction data
PB International Union of Crystallography
SN 2056-9890
YR 2008
FD 2008
LK http://hdl.handle.net/10347/23132
UL http://hdl.handle.net/10347/23132
LA eng
NO Soengas, Raquel G. ; Valencia, Laura ; Estévez, Juan C. ; Estévez, Ramón J. (2008). Ethyl 1-O-tert-butyldimethylsilyl-2,3-O-isopropylidene-5-[(2′S)-tetrahydropyran-2-yloxy]-D-glycero-α-D-manno-heptofuronate. " Acta Crystallographica Section E",  E64, o1478
NO We gratefully acknowledge the Spanish Education Secretary and the Xunta de Galicia for financial support and the Spanish Education Secretary for a grant to RGS
DS Minerva
RD 28 abr 2026