RT Journal Article
T1 NIR-responsive nano-holed titanium alloy surfaces: a photothermally activated antimicrobial biointerface
A1 Pistonesi, Denise B.
A1 Belén, Federico
A1 Ruso Beiras, Juan Manuel
A1 Centurión, María Eugenia
A1 Sica, María Gabriela
A1 Pistonesi, Marcelo  F.
A1 Messina, Paula V.
K1 Near-infrared radiation
K1 Ti6Al4V alloy
K1 Silver nanoparticles
K1 Antibacterial properties
K1 Photothermal conversion
K1 Optical band gap
AB Among external stimuli-responsive therapy approaches, those using near infrared (NIR) light irradiation have attracted significant attention to treat bone-related diseases and bone tissue regeneration. Therefore, the development of metallic biomaterials sensitive to NIR stimuli is an important area of research in orthopaedics. In this study, we have generated in situ prism-shaped silver nanoparticles (p-AgNPs) in a biomorphic nano-holed TiO2 coating on a Ti6Al4V alloy (a-Ti6Al4V). Insertion of p-AgNPs does not disturb the periodically arranged sub-wavelength-sized unit cell on the a-Ti6Al4V dielectric structure, while they exacerbate its peculiar optical response, which results in a higher NIR reflectivity and high efficiency of NIR photothermal energy conversion suitable to bacterial annihilation. Together, these results open a promising path toward strategic bone therapeutic procedures, providing novel insights into precision medicine
PB Royal Society of Chemistry
YR 2024
FD 2024-08-05
LK https://hdl.handle.net/10347/43448
UL https://hdl.handle.net/10347/43448
LA eng
NO Pistonesi, D. B., Belén, F., Ruso, J. M., Centurión, M. E., Sica, M. G., Pistonesi, M. F. and Messina, P. V. (2024). NIR-responsive nano-holed titanium alloy surfaces: a photothermally activated antimicrobial biointerface. J. Mater. Chem. B, 2024,12, 8993-9004
NO Universidad Nacional del Sur [UNS, PGI 24/Q131], Consejo Nacional de Investigaciones Científicas y Técnicas [CONICET, PIP 11220210100126CO] and Agencia Nacional de Promoción Científica y Tecnológica [ANPCyT, PICT-2021-I-A-00108]
NO Xunta de Galicia [ED431B 2022/36]
DS Minerva
RD 27 abr 2026