RT Journal Article
T1 Dietary Exposure Estimation to Chemicals Transferred from Milk and Dairy Products Packaging Materials in Spanish Child and Adolescent Population
A1 Lestido Cardama, Antía
A1 Sendón García, Raquel
A1 Bustos, Juana
A1 Lomo, M. Luisa
A1 Paseiro Losada, Perfecto
A1 Rodríguez Bernaldo de Quirós, Ana Isabel
K1 Exposure estimation
K1 TDS-like investigation
K1 Food packaging
K1 Dairy products
K1 Composite food samples
K1 GC-MS
AB Packaging materials are subject to risk assessment since they can transfer their components to the food, and they may constitute a risk for the consumers’ health. Therefore, estimating the exposure to chemicals migrating from packaging is required. In this study, a novel approach based on a total diet study (TDS)-like investigation to evaluate the exposure to chemicals transferred from the packaging was presented. The proposed methodology involved a non-targeted gas chromatography coupled to mass spectrometry (GC-MS) method to identify potential migrants and the determination of the migrants in composite food samples. The method was applied to evaluate the dietary exposure to chemicals from food packaging materials used for milk and dairy products in the Spanish child and adolescent populations. Several migrants identified in packaging materials were selected to determine their concentration in composite food samples. These chemicals included diethyl phthalate (DEP), diisobutyl phthalate (DIBP), dibutyl phthalate (DBP), bis(2ethylhexyl) phthalate (DEHP), benzophenone (BP), 1,3-diphenylpropane (1,3-DPP), and bis(2-ethylhexyl) terephthalate (DEHT). The method exhibited a good sensitivity (limit of detection, LOD ≤ 0.05 µg/g) and a satisfactory recovery (78.4-124%). Finally, the exposure was estimated using the Spanish national dietary survey ENALIA. Phthalates DBP and DEHP showed the highest mean exposure, ranging from 2.42 (10–17 years)–4.40 (12–35 months) and 1.35 (10–17 years)–4.07 (12–35 months) µg/kg bw/day for DBP and DEHP, respectively
PB MDPI
YR 2020
FD 2020
LK http://hdl.handle.net/10347/24054
UL http://hdl.handle.net/10347/24054
LA eng
NO Lestido-Cardama, A.; Sendón, R.; Bustos, J.; Lomo, M.L.; Losada, P.P.; de Quirós, A.R.B. Dietary Exposure Estimation to Chemicals Transferred from Milk and Dairy Products Packaging Materials in Spanish Child and Adolescent Population. Foods 2020, 9, 1554
NO This study was financially supported by the Ministerio de Economía y Competitividad, by Fondo Europeo de Desarrollo Regional (FEDER), and by Agencia Estatal de Investigación Ref.No. AGL2015-69609-P “MIGRAEXPO” (MINECO/FEDER, UE)
DS Minerva
RD 24 abr 2026