RT Journal Article
T1 Advanced Proteomic and Bioinformatic Tools for Predictive Analysis of Allergens in Novel Foods
A1 Moreira Martínez, Ramón Felipe
A1 López-Pedrouso, María
A1 Lorenzo, José M.
A1 Franco Ruiz, Daniel
A1 Dios Alché, Juan de
K1 Novel proteins
K1 Food safety
K1 Allergenicity
K1 Mass spectrometry
K1 Omic technologies
AB In recent years, novel food is becoming an emerging trend increasingly more demanding in developed countries. Food proteins from vegetables (pulses, legumes, cereals), fungi, bacteria and insects are being researched to introduce them in meat alternatives, beverages, baked products and others. One of the most complex challenges for introducing novel foods on the market is to ensure food safety. New alimentary scenarios drive the detection of novel allergens that need to be identified and quantified with the aim of appropriate labelling. Allergenic reactions are mostly caused by proteins of great abundance in foods, most frequently of small molecular mass, glycosylated, watersoluble and with high stability to proteolysis. The most relevant plant and animal food allergens, such as lipid transfer proteins, profilins, seed storage proteins, lactoglobulins, caseins, tropomyosinsand parvalbumins from fruits, vegetables, nuts, milk, eggs, shellfish and fish, have been investigated. New methods for massive screening in search of potential allergens must be developed, particularly concerning protein databases and other online tools. Moreover, several bioinformatic tools based on sequence alignment, motif identification or 3-D structure predictions should be implemented as well. Finally, targeted proteomics will become a powerful technology for the quantification of these hazardous proteins. The ultimate objective is to build an effective and resilient surveillance network with this cutting-edge technology.
PB MDPI
YR 2023
FD 2023-05-13
LK http://hdl.handle.net/10347/31653
UL http://hdl.handle.net/10347/31653
LA eng
NO López-Pedrouso, M., Lorenzo, J. M., Alché, J., Moreira, R., Franco, D. (2023). Advanced Proteomic and Bioinformatic Tools for Predictive Analysis of Allergens in Novel Foods. "Biology", vol. 12(5), 714
DS Minerva
RD 25 abr 2026