RT Journal Article
T1 Cell-Free microRNAs as potential oral cancer biomarkers: from diagnosis to therapy
A1 Rapado González, Óscar
A1 López López, Rafael
A1 López Cedrún, José Luis
A1 Triana Martínez, Gabriel
A1 Muinelo Romay, Laura
A1 Suárez Cunqueiro, María Mercedes
K1 MicroRNAs
K1 Oral cancer
K1 Liquid biopsy
K1 Biomarkers
K1 Epigenetic
AB Oral cavity cancer is the most frequent malignancy of the head and neck. Unfortunately,despite educational interventions for prevention and early diagnosis, oral cancer patients are oftendiagnosed in advanced stages associated with poor prognosis and life expectancy. Therefore, there isan urgent need to find noninvasive biomarkers to improve early detection of this tumor. Liquid biopsyhas emerged as a valuable tool in medical oncology which provides new horizons for improvingclinical decision making. Notably, cell-free microRNAs (miRNAs), a class of short non-coding RNAs,are emerging as novel noninvasive cancer biomarkers. Here, we provide an overview of the potentialclinical application of cell-free miRNAs as diagnostic, prognostic, and therapeutic biomarkers inoral cancer
PB MDPI
YR 2019
FD 2019
LK http://hdl.handle.net/10347/21251
UL http://hdl.handle.net/10347/21251
LA eng
NO Rapado-González, Ó.; López-López, R.; López-Cedrún, J.L.; Triana-Martínez, G.; Muinelo-Romay, L.; Suárez-Cunqueiro, M.M. Cell-Free microRNAs as Potential Oral Cancer Biomarkers: From Diagnosis to Therapy. Cells 2019, 8, 1653
DS Minerva
RD 24 abr 2026