RT Journal Article
T1 Psychological factors and premenstrual syndrome: A Spanish case-control study
A1 Fernández, María del Mar
A1 Regueira Méndez, Carlos Manuel Pastor
A1 Takkouche, Bahi
AB Objective : To assess whether the psychological variables perceived stress, neuroticism and coping strategies, are associated with Premenstrual Syndrome (PMS) and Premenstrual Dysphoric Syndrome (PMDD).Design : Case-control study with incident cases using the Spanish public healthcare system.Setting3 major public hospitals and one family counseling and planning center.PopulationWomen consulting for troubles related to menstruation and for other motives such as screening for uterine cancer, contraception counselling or desire for pregnancy.Methods : Logistic regression.Main outcome measures : Odds of PMS and PMDD.Results : 285 PMS and 285 age-matched controls, as well as 88 PMDD cases and 176 controls participated in the study. Medium and high levels of perceived stress were associated with an increase in the odds of PMS (Odds Ratio (OR) = 2.49; 95%CI: 1.41–4.39 and OR = 4.90; 95%CI: 2.70–8.89, respectively). For PMDD the results were: OR = 2.61; 95%CI: 1.35–5.05 and OR = 5.79; 95%CI: 2.63–12.76, respectively.Subjects with medium and high levels of neuroticism were also at higher odds of suffering from PMS (OR = 2.53; 95%CI: 1.06–6.06 and OR = 8.05; 95%CI: 3.07–2.12, respectively). For PMDD, the results were OR = 3.70; 95%CI: 1.27–10.77 and 5.73: 95%CI: 1.96–16.77, respectively.High levels in the large majority of coping strategies were also associated with increased odds of PMS and PMDD.Conclusions : Psychological factors including perceived stress, neuroticism and coping strategies are strongly related to PMS/PMDD. This association is unlikely to be due to confounding or misclassification bias. A reverse causation process cannot be ruled out although its likelihood is remote.
PB PLOS
YR 2019
FD 2019
LK http://hdl.handle.net/10347/21586
UL http://hdl.handle.net/10347/21586
LA eng
NO Del Mar Fernández, M., Regueira-Méndez, C., & Takkouche, B. (2019). Psychological factors and premenstrual syndrome: A spanish case-control study. PloS One, 14(3), e0212557. doi:10.1371/journal.pone.0212557
DS Minerva
RD 24 abr 2026