RT Journal Article
T1 Assembly of a Ternary Metallopeptide Complex at Specific DNA Sites Mediated by an AT‐Hook Adaptor
A1 Learte Aymamí, Soraya
A1 Rodríguez Villar, Jéssica
A1 Vázquez Sentís, Marco Eugenio
A1 Mascareñas Cid, José Luis
K1 Chemical biology
K1 DNA binding
K1 Molecular recognition
K1 Peptides
K1 Supramolecular chemistry
AB The nickel(II)‐mediated self‐assembly of a multimeric DNA binder is described. The binder is composed of two metal‐chelating peptides derived from a bZIP transcription factor (brHis2) and one short AT‐hook domain equipped with two bipyridine ligands (HkBpy2). These peptides reversibly assemble in the presence of NiII ions at selected DNA sequences of 13 base pairs
PB Wiley
SN 0947-6539
YR 2020
FD 2020
LK http://hdl.handle.net/10347/23208
UL http://hdl.handle.net/10347/23208
LA eng
NO S. Learte-Aymamí, J. Rodríguez, M. E. Vázquez, J. L. Mascareñas, Chem. Eur. J. 2020 , 26 , 8875.
NO Financial support from the Spanish grants SAF2016‐76689‐R, RTI2018‐099877‐B‐I00, Orfeo‐cinqa network CTQ2016‐81797‐REDC, the Xunta de Galicia (2015‐CP082, ED431C‐2017/19 and Centro Singular de Investigación de Galicia accreditation 019–2022, ED431G 2019/03), the European Union (European Regional Development Fund—ERDF), and the European Research Council (Advanced Grant No. 340055) are gratefully acknowledged. S.L.‐A. thanks the Spanish MINECO for her FPI fellowship (BES‐2017‐080555); J.R. thanks the Xunta de Galicia for her PhD fellowship
DS Minerva
RD 25 abr 2026