RT Dissertation/Thesis
T1 Study of the variable genome of Photobacterium damselae: acquisition of new metabolic traits, antimicrobial resistance and a novel virulence plasmid
A1 Suleiman Salameh Abushattal, Saqr
K1 Photobacterium damselae
K1 plasmid
K1 antimicrobial resistance
K1 virulence
K1 aquaculture
K1 bacteria
K1 T3SS
K1 sucrose
AB The two subspecies of Photobacterium damselae, namely subsp. damselaeand subsp. piscicida, are pathogenic for diverse fish species of financial importance in marine aquaculture. In thepresent thesis we have characterized the variable genome in these two subspecies, which proved to be highlydiverse. We have demonstrated that horizontal gene transfer has played a major role in the acquisition of the abilityto metabolize sucrose, and in antimicrobial resistance in the subspecies damselae. Notably, this study has unveiledthe existence of a novel, highly unstable virulence plasmid, encoding a Type III secretion system (T3SS) that ishighly prevalent in the subspecies piscicida, and which constitutes a new virulence factor in this pathogen.
YR 2021
FD 2021
LK http://hdl.handle.net/10347/26498
UL http://hdl.handle.net/10347/26498
LA eng
DS Minerva
RD 24 abr 2026