RT Journal Article
T1 One Health Approach: An Overview of Q Fever in Livestock, Wildlife and Humans in Asturias (Northwestern Spain)
A1 Espí, Alberto
A1 Cerro, Ana del
A1 Oleaga, Alvaro
A1 Rodríguez Pérez, Mercedes
A1 López Sández, Ceferino Manuel
A1 Hurtado, Ana
A1 Rodríguez Martínez, Luís D.
A1 Barandika, Jesús F.
A1 García Pérez, Ana L.
K1 Q fever
K1 Coxiella burnetii
K1 Seroprevalence
K1 Ruminants
K1 Wildlife
K1 Humans
K1 Dust
K1 Aerosols
AB This study aimed to investigate the seroprevalence of C. burnetii in domestic ruminants, wild ungulates, as well as the current situation of Q fever in humans in a small region in northwestern Spain where a close contact at the wildlife–livestock–human interface exists, and information on C. burnetii infection is scarce. Seroprevalence of C. burnetii was 8.4% in sheep, 18.4% in cattle, and 24.4% in goats. Real-time PCR analysis of environmental samples collected in 25 livestock farms detected Coxiella DNA in dust and/or aerosols collected in 20 of them. Analysis of sera from 327 wild ungulates revealed lower seroprevalence than that found in domestic ruminants, with 8.4% of Iberian red deer, 7.3% chamois, 6.9% fallow deer, 5.5% European wild boar and 3.5% of roe deer harboring antibodies to C. burnetii. Exposure to the pathogen in humans was determined by IFAT analysis of 1312 blood samples collected from patients admitted at healthcare centers with Q fever compatible symptoms, such as fever and/or pneumonia. Results showed that 15.9% of the patients had IFAT titers ≥ 1/128 suggestive of probable acute infection. This study is an example of a One Health approach with medical and veterinary institutions involved in investigating zoonotic diseases
PB MDPI
YR 2021
FD 2021
LK http://hdl.handle.net/10347/26259
UL http://hdl.handle.net/10347/26259
LA eng
NO Animals 2021, 11(5), 1395; https://doi.org/10.3390/ani11051395
NO This work was funded by INIA—Spanish National Institute for Agricultural and Food Research and Technology (RTA2017-00055-C02-02), the European Regional Development Funds (ERDF), and PCTI 2018–2020 (GRUPIN: IDI2018-000237)
DS Minerva
RD 30 abr 2026