RT Journal Article T1 Cognitive frailty: an update A1 Facal Mayo, David A1 Burgo, Clara A1 Spuch, Carlos A1 Gaspar, Pedro A1 Campos Magdaleno, María K1 Frailty K1 Subjective cognitive decline K1 Cognitive reserve K1 Biomarkers K1 Physical activity K1 Dual-task intervention K1 Multicomponent intervention programs K1 Mild cognitive impairment AB This review article provides an update of the empirical research on cognitive fragility conducted in the last four years. The studies retrieved were classified in four different categories. The first category includes articles relating cognitive frailty to cognitive reserve and which continue to highlight the importance of educational level. The second category includes recent research on cognitive fragility biomarkers, involving neuroimaging, metabolism and, in a novel way, microbiota. The third category includes research on how cognitive frailty is related to motor development and physical functioning, exploring e.g. the use of technology to study motor markers of cognitive frailty. Finally, in the fourth category, research clarifying the difference between reversible frailty and potentially reversible cognitive frailty has led to new interventions aimed at reducing cognitive frailty and preventing negative health outcomes. Interventions based on physical activity and multicomponent interventions are particularly emphasized. In addition, recent research explores the long-term effects of dual interventions in older adults living in nursing homes. In summary, research on cognitive frailty has increased in recent years, and applied aspects have gained importance PB Frontiers Media SN 1664-1078 YR 2021 FD 2021 LK http://hdl.handle.net/10347/27434 UL http://hdl.handle.net/10347/27434 LA eng NO Facal D, Burgo C, Spuch C, Gaspar P and Campos-Magdaleno M (2021) Cognitive Frailty: An Update. Front. Psychol. 12:813398 NO This work was financially supported through FEDER founds (A way to make Europe) by the Spanish AEI (doi: 10.13039/501100011033; Refs. PID2020-114521RB-C21 and PSI2017-89389-C2-1-R) and by the Galician Government (Consellería de Cultura, Educación e Ordenación Universitaria; GI-1807-USC: Ref. ED431C 2021/04). CB was supported by a Research Initiation Grant from the University of Santiago de Compostela, co-financed by Banco Santander. The funders were not involved in the study design, collection, analysis, interpretation of data, the writing of this article or the decision to submit it for publication DS Minerva RD 22 abr 2026