RT Journal Article
T1 Magnetic hyperthermia enhancement in iron-based materials driven by carbon support interactions
A1 Vizcaíno Anaya, Lucía
A1 Herreros Lucas, Carlos
A1 Vila Fungueiriño, José Manuel
A1 Giménez López, María del Carmen
K1 Carbon supports
K1 Iron magnetic nanoparticles
K1 Magnetic hyperthermia
K1 Nanoparticle-carbon interactions
K1 Specific absorption rates
AB Magnetic hyperthermia (MH) shows great potential in clinical applications because of its very localized action and minimal side effects. Because of their high saturation magnetization values, reduced forms of iron are promising candidates for MH. However, they must be protected in order to overcome their toxicity and instability (i. e., oxidation) under biological conditions. In this work, a novel methodology for the protection of iron nanoparticles through confinement within graphitic carbon layers after thermal treatment of preformed nanoparticles supported on carbon is reported. We demonstrate that the size and composition of the nascent confined iron nanoparticles, as well as the thickness of their protective carbon layer can be controlled by selecting the nature of the carbon support. Our findings reveal that a higher nanoparticle–carbon interaction, mediated by the presence of oxygen-containing groups, induces the formation of small and well-protected α-Fe-based nanoparticles that exhibit promising results towards MH based on their enhanced specific absorption rate values
PB Wiley
SN 0947-6539
YR 2022
FD 2022
LK http://hdl.handle.net/10347/29708
UL http://hdl.handle.net/10347/29708
LA eng
NO L. Vizcaíno-Anaya, C. Herreros-Lucas, J. M. Vila-Fungueiriño, M. del Carmen Giménez-López, Chem. Eur. J. 2022, 28, e202201861
NO Agencia Estatal de Investigación. Grant Numbers: RTI2018-101097-A-I00, RyC-2016-20258, PID2021-127341OB-I00. European Research Council. Grant Numbers: 679124, 966743. Consellería de Cultura, Educación e Ordenación Universitaria, Xunta de Galicia. Grant Numbers: 2019-2022, ED431G 2019/03, ED431B 2021/13. Ministerio de Ciencia, Innovación y Universidades. Grant Number: FPU2020
DS Minerva
RD 23 abr 2026