RT Dissertation/Thesis
T1 Development of aerogel-based formulations for regenerative medicine
A1 Iglesias-Mejuto, Ana
K1 ingeniería de tejidos ósea
K1 aerogel
K1 scaffold
K1 impresión 3D
K1 medicina regenerativa
AB The prevalence of infections and the absence of tissueregeneration motivate the study of new strategies for themanufacturing of bone implants. Dual porosity and drugloading into scaffolds are needed to promote the long-term newbone tissue formation while the customization of the implants isrequired in personalized medicine. In this PhD Thesis, adual processing strategy was developed by combining the 3Dprintingand the supercritical fluid technologies tomanufacture 3D-printed and sterile aerogels for bone tissueengineering applications. Furthermore, the monitoring ofaerogels and their degradation products after implantation wasstudied in vivo for the first time. This work aims to endowbioaerogels with new capabilities while preserving their safetyprofile and advanced physicochemical performance.
YR 2024
FD 2024
LK http://hdl.handle.net/10347/34957
UL http://hdl.handle.net/10347/34957
LA eng
DS Minerva
RD 28 abr 2026