RT Journal Article
T1 An on-surface Diels–Alder reaction
A1 Castro Esteban, Jesús
A1 Albrecht, Florian
A1 Fatayer, Shadi
A1 Pérez Meirás, María Dolores
A1 Gross, Leo
A1 Peña Gil, Diego
K1 Bond-resolved AFM
K1 Cycloaddition
K1 Diels–Alder reaction
K1 On-surface synthesis
K1 Polycyclic aromatic hydrocarbons
AB The Diels–Alder reaction is one of the most popular reactions in organic chemistry. However, its use in the field of on-surface synthesis is hampered by the spatial restrictions of this cycloaddition reaction. Herein we selected a cyclic strained triyne to demonstrate an on-surface hexadehydro-Diels–Alder reaction in a single molecule. The reaction was studied in detail by means of atomic force microscopy (AFM) with CO-functionalized tips. Our results pave the way to use this iconic pericyclic reaction for on-surface synthesis, introducing the concept of atom economy in the field
PB Wiley
SN 1433-7851
YR 2021
FD 2021
LK http://hdl.handle.net/10347/29052
UL http://hdl.handle.net/10347/29052
LA eng
NO Angew. Chem. Int. Ed. 2021, 60, 26346 – 26350. https://doi.org/10.1002/anie.202110311
NO We thank Rolf Allenspach and Enrique Guitián for discussions. We thank the European Union (Project SPRING, contract no. 863098), the ERC grant AMSEL (682144), the Spanish Agencia Estatal de Investigación (PID2019-107338RB-C62, PID2019-110037GB-I00 and PCI2019-111933-2), Xunta de Galicia (Centro de Investigación de Galicia accreditation 2019–2022, ED431G 2019/03) and the European Regional Development Fund-ERDF for financial support
DS Minerva
RD 24 abr 2026