RT Dissertation/Thesis T1 Molecular Characterization of Extended-Spectrum beta-Lactamase-Producing Escherichia coli and Clones Causing Extraintestinal Infections in Humans. Animals as Reservoir of High-Risk E. coli Clones Pathogenic for Humans A1 Flament Simon, Saskia Camille K1 Escherichia coli K1 clonal structure K1 virulence genes K1 antibiotic resistance K1 high-risk clones K1 plasmidome AB Escherichia coli is the leading cause of urinary tract and bloodstreaminfections in humans and animals. The treatment of these infections has been seriously complicated by theappearance of multidrug-resistant isolates and especially by the rapid dissemination of extended-spectrum betalactamase-producing E. coli (ESBLEC).The present doctoral thesis includes six studies in which we evaluated the prevalence, the phenotypic and thegenotypic characteristics of sequence type 131 (ST131) strains and other high-risk clones among E. coli strainsisolated from patients with extraintestinal infections. We also study animals (pigs and dogs) as reservoirs for ST131strains and other high-risk clones. YR 2021 FD 2021 LK http://hdl.handle.net/10347/26039 UL http://hdl.handle.net/10347/26039 LA eng DS Minerva RD 24 abr 2026