RT Journal Article
T1 3D Printed Tablets (Printlets) with Braille and Moon Patterns for Visually Impaired Patients
A1 Awad, Atheer
A1 Yao, Aliya
A1 Trenfield, Sarah J.
A1 Goyanes Goyanes, Álvaro
A1 Gaisford, Simon
A1 Basit, Abdul W.
K1 Three-Dimensional Printing
K1 3D Printed Drug Products
K1 Orally Disintegrating Tablets
K1 Personalised Medicines
K1 Personalized Pharmaceuticals
K1 Blindness
K1 Visual Deprivation
K1 Touch-Reading Compliance
K1 Tactile Patterns
K1 Sight Loss
AB Visual impairment and blindness affects 285 million people worldwide, resulting in a high public health burden. This study reports, for the first time, the use of three-dimensional (3D) printing to create orally disintegrating printlets (ODPs) suited for patients with visual impairment. Printlets were designed with Braille and Moon patterns on their surface, enabling patients to identify medications when taken out of their original packaging. Printlets with different shapes were fabricated to offer additional information, such as the medication indication or its dosing regimen. Despite the presence of the patterns, the printlets retained their original mechanical properties and dissolution characteristics, wherein all the printlets disintegrated within ~5 s, avoiding the need for water and facilitating self-administration of medications. Moreover, the readability of the printlets was verified by a blind person. Overall, this novel and practical approach should reduce medication errors and improve medication adherence in patients with visual impairment
PB MDPI
YR 2020
FD 2020
LK http://hdl.handle.net/10347/21915
UL http://hdl.handle.net/10347/21915
LA eng
NO Awad, A.; Yao, A.; Trenfield, S.J.; Goyanes, A.; Gaisford, S.; Basit, A.W. 3D Printed Tablets (Printlets) with Braille and Moon Patterns for Visually Impaired Patients. Pharmaceutics 2020, 12, 172.
NO The authors thank the Engineering and Physical Sciences Research Council (EPSRC), UK, for theirfinancial support (EP/L01646X)
DS Minerva
RD 24 abr 2026