RT Journal Article
T1 Differential associations between distinct components of cognitive and physical function in middle-aged and older adults
A1 Facal Mayo, David
A1 Picón Prado, Eduardo
A1 Blumen, Helena M.
A1 Lojo Seoane, Cristina
A1 Nieto Vieites, Ana
A1 Stern, Yaakov
A1 Pereiro Rozas, Arturo X.
K1 Verbal learning
K1 Executive function
K1 Mobility
K1 Timed-Up and Go
K1 Grip stregth
K1 Non-parametric analysis
AB Background: Cognitive and physical functions share certain age-related patterns of change, including slowed processing speed and movement. Both functions are multifaceted, and the association between them can be affected by the type of measurement considered. This study examined one-to-one relationships between cognitive and physical functions, using data from the Compostela Aging Study. Methods: A total of 267 middle-aged and older individuals without cognitive impairment were included in the study (mean age 65.57, 75.7% women). The relationship between cognitive and physical performance was examined using Spearman’s rho, adjusted for age and sex. Results: Standing up, sitting down and total times in the Timed-Up and Go test were significantly correlated with performance on the Trail-Making and phonological fluency tests. Turning time in the Timed-Up and Go test and self-reported physical activity were correlated with performance on the Spanish version of the California Verbal Learning Test. Grip strength was correlated with performance on the Counting Span task. Conclusions: This study adds evidence to the one-to-one relationship between cognitive and physical function in a subclinical cohort of middle-aged and older adults
PB Multidisciplinary Digital Publishing Institute
SN 2076-3425
YR 2025
FD 2025-12-27
LK https://hdl.handle.net/10347/45954
UL https://hdl.handle.net/10347/45954
LA eng
NO Facal, D., Picón, E., Blumen, H. M., Lojo-Seoane, C., Nieto-Vieites, A., Stern, Y., & Pereiro, A. X. (2026). Differential Associations Between Distinct Components of Cognitive and Physical Function in Middle-Aged and Older Adults. Brain Sciences, 16(1), 40. https://doi.org/10.3390/brainsci16010040
NO The CompAS study is supported though FEDER funds provided by the Spanish National Research Agency (Spanish Ministry of Science, Innovation and Universities) (Refs. PID2020-114521RB-C21 and PID2023-151659OB-C21) and by the Galician Government (Ref. ED431C 2025/14; GI-1807-USC). The current manuscript was developed during a research internship of the first author at Columbia University Irving Medical Center funded by the Spanish Ministry of Science, Innovation and Universities (ref. PRX22/00175) and supported by the Fulbright Visiting Scholar Program
DS Minerva
RD 7 jun 2026