RT Journal Article
T1 Longitudinal Assessment of Verbal Learning and Memory in Amnestic Mild Cognitive Impairment: Practice Effects and Meaningful Changes
A1 Campos Magdaleno, María
A1 Facal Mayo, David
A1 Lojo Seoane, Cristina
A1 Pereiro Rozas, Arturo X.
A1 Juncos Rabadán, Onésimo
K1 California verbal learning test
K1 Subjective memory complaints
K1 Longitudinal design
K1 Standardized regression based methods
K1 Repeated assessments
AB Objectives: To identify learning effects and meaningful changes in amnestic mild cognitive impairment (aMCI) at a follow-up assessment.Method: The Spanish version of the California Verbal Learning Test (CVLT) was administered to a sample of 274 adults of age over 50 years with subjective memory complains (SMC), including single and multiple domain aMCI groups and participants with SMC but without cognitive impairment (SMC group). The Wilcoxon test was used to compare results at baseline and after 18 months in short and long recall, and standardized regression-based (SRB) methods were used to study meaningful changes.Results: Scores were significantly higher at follow-up for short and long-delayed recall in all groups indicating generalized practice effect. SRB scores indicated a significant decline in recall in a higher proportion of participants with aMCI than in SMC group.Discussion: Patients with multiple and single domain aMCI benefit from practice in a verbal learning memory test. The SRB approach revealed a higher incidence of meaningful decline in short and long-delay recall and recognition in the aMCI groups than in the SMC group. Specifically, compared to SMC participants, single-domain aMCI individuals declined in a higher proportion in all measures, and multiple-domain aMCI individuals in long delay free recall
PB Frontiers Media
YR 2017
FD 2017
LK http://hdl.handle.net/10347/22511
UL http://hdl.handle.net/10347/22511
LA eng
NO Campos-Magdaleno M, Facal D, Lojo-Seoane C, Pereiro AX and Juncos-Rabadán O (2017) Longitudinal Assessment of Verbal Learning and Memory in Amnestic Mild Cognitive Impairment: Practice Effects and Meaningful Changes. Front. Psychol. 8:1231
NO This work was financially supported by the Spanish Directorate General of Scientific and Technical Research (Project PSI2014-55316-C3-1-R) and by the Galician Government (Consellería de Cultura, Educación e Ordenación Universitaria; axudas para a consolidación e Estruturación de unidades de investigación competitivas do Sistema universitario de Galicia; GPC2014/047) through FEDER founds
DS Minerva
RD 23 abr 2026