RT Journal Article T1 Bone Loss at Implant with Titanium Abutments Coated by Soda Lime Glass Containing Silver Nanoparticles: A Histological Study in the Dog A1 Martínez Insua, Arturo A1 Guitián Rivera, Francisco A1 López Píriz, Roberto A1 Bartolomé, José F. A1 Cabal, Belén A1 Esteban Tejeda, Leticia A1 Torrecillas, Ramón A1 Moya, José S. K1 Coatings K1 Silver K1 Nanoparticles K1 Ephitelium K1 Histology K1 Inflammation K1 Dogs K1 Surface treatments AB The aim of the present study was to evaluate bone loss at implants connected to abutments coated with a soda-lime glass containing silver nanoparticles, subjected to experimental peri-implantitis. Also the aging and erosion of the coating in mouth was studied. Five beagle dogs were used in the experiments. Three implants were placed in each mandible quadrant: in 2 of them, Glass/n-Ag coated abutments were connected to implant platform, 1 was covered with a Ti-mechanized abutment. Experimental peri-implantitis was induced in all implants after the submarginal placement of cotton ligatures, and three months after animals were euthanatized. Thickness and morphology of coating was studied in abutment cross-sections by SEM. Histology and histo-morphometric studies were carried on in undecalfied ground slides. After the induced peri-implantitis: 1.The abutment coating shown losing of thickness and cracking. 2. The histometry showed a significant less bone loss in the implants with glass/n-Ag coated abutments. A more symmetric cone of bone resorption was observed in the coated group. There were no significant differences in the peri-implantitis histological characteristics between both groups of implants. Within the limits of this in-vivo study, it could be affirmed that abutments coated with biocide soda-lime-glass-silver nanoparticles can reduce bone loss in experimental peri-implantitis. This achievement makes this coating a suggestive material to control peri-implantitis development and progression. PB PLOS YR 2014 FD 2014 LK http://hdl.handle.net/10347/22459 UL http://hdl.handle.net/10347/22459 LA eng NO Martinez A, Guitián F, López-Píriz R, Bartolomé JF, Cabal B, Esteban-Tejeda L, et al. (2014) Bone Loss at Implant with Titanium Abutments Coated by Soda Lime Glass Containing Silver Nanoparticles: A Histological Study in the Dog. PLoS ONE 9(1): e86926. https://doi.org/10.1371/journal.pone.0086926 NO This work was supported by the Spanish Ministry of Science and Innovation (MICINN) under the projects MAT2009-14542-C02-01 and MAT2012-38645.B. Cabal thanks the CSIC JAE-Doc Program for a postdoctoral contract DS Minerva RD 24 abr 2026