RT Journal Article
T1 Gold(I)‐Catalyzed Cascade Cycloadditions between Allenamides and Carbonyl‐Tethered Alkenes: An Enantioselective Approach to Oxa‐Bridged Medium‐Sized Carbocycles
A1 Faustino, Hélio
A1 Alonso García, Isaac
A1 Mascareñas Cid, José Luis
A1 López García, Fernando
K1 Annulation
K1 Cascade reactions
K1 Homogeneous catalysis
K1 Enantioselective
K1 Gold
AB Gold standard: Allenamides react with aldehydes or ketones having γ, δ, or ε alkenyl groups, upon activation with suitable gold catalysts, to provide oxa-bridged systems containing seven- to nine-membered carbocycles, in a formal cascade cycloaddition. By using chiral phosphoramidite/gold or bisphosphine/gold catalysts it is possible to obtain the oxa-bridged seven- and eight-membered rings with good to high enantioselectivity
PB Wiley
SN 1433-7851
YR 2013
FD 2013
LK http://hdl.handle.net/10347/18483
UL http://hdl.handle.net/10347/18483
LA eng
NO Faustino, H. , Alonso, I. , Mascareñas, J. L. and López, F. (2013), Gold(I)‐Catalyzed Cascade Cycloadditions between Allenamides and Carbonyl‐Tethered Alkenes: An Enantioselective Approach to Oxa‐Bridged Medium‐Sized Carbocycles. Angew. Chem. Int. Ed., 52: 6526-6530. doi:10.1002/anie.201302713
NO This is the peer reviewed version of the following article: Faustino, H. , Alonso, I. , Mascareñas, J. L. and López, F. (2013), Gold(I)‐Catalyzed Cascade Cycloadditions between Allenamides and Carbonyl‐Tethered Alkenes: An Enantioselective Approach to Oxa‐Bridged Medium‐Sized Carbocycles. Angew. Chem. Int. Ed., 52: 6526-6530, which has been published in final form at https://doi.org/10.1002/anie.201302713. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions
NO This work was supported by the Spanish MINECO, (SAF2010‐20822‐C02‐01/02, and Consolider‐Ingenio 2010 CSD2007‐00006), ERDF funds, and Xunta de Galicia (INCITE09209084PR, GRC2010/12). H.F. acknowledges the Fundação para a Ciência e Tecnologia (Portugal) and POPH/FSE for a PhD grant (SFRH/BD/60214/2009)
DS Minerva
RD 1 may 2026