RT Journal Article
T1 Palladium-Catalyzed Formal (5 + 2) Annulation between ortho-Alkenylanilides and Allenes
A1 Cendón Mariño, Borja
A1 Casanova González, Noelia
A1 Comanescu, Cezar
A1 García Fandiño, Rebeca
A1 Seoane Fernández, Andrés
A1 Gulías Costa, Moisés
A1 Mascareñas Cid, José Luis
K1 Palladium-catalyzed
K1 Ortho- alkenylanilides
K1 Allenes
AB 2-Alkenyltriflylanilides react with allenes upon treatment with catalytic amounts of Pd(OAc)2 and Cu(II) to give highly valuable 2,3-dihydro-1H-benzo[b]azepines, in good yields, and with very high regio- and diastereoselectivities. Density functional theory (DFT) calculations suggest that the C–H activation of the alkenylanilide involves a classical concerted metalation–deprotonation (CMD) mechanism
PB American Chemical Society
SN 1523-7060
YR 2017
FD 2017-03-27
LK http://hdl.handle.net/10347/15444
UL http://hdl.handle.net/10347/15444
LA eng
NO Cendón, B., Casanova, N., Comanescu, C., Garcí­a-Fandiño, R., Seoane, A., Gulías, M. & Mascareñas, J.L. 2017, "Palladium-Catalyzed Formal (5 + 2) Annulation between ortho-Alkenylanilides and Allenes", Organic letters, vol. 19, no. 7, pp. 1674-1677
NO This is the peer reviewed version of the following article: Borja Cendón, Noelia Casanova, Cezar Comanescu, Rebeca García-Fandiño, Andrés Seoane, Moisés Gulías* and José L. Mascareñas*, Palladium-Catalyzed Formal (5+2) annulation between ortho-Alkenylanilides and Allenes. Org. Lett. 2017, 19, 1674-1677 [DOI: ]. This article may be used for non commercial purposes in accordance with American Chemical Society Terms and Conditions for self-archiving
NO This work has received financial support from Spanish grants(SAF2013-41943-R, SAF2016-76689-R, CTQ2015-74621-JINand CTQ2016-77047-P), the Consellería de Cultura, Educación eOrdenación Universitaria (GRC2013-041, 2015-CP082 and CentroSingular de Investigación de Galicia accreditation 2016-2019,ED431G/09), the European Regional Development Fund (ERDF),and the European Research Council (Advanced Grant No.340055). R. G.-F. thanks a FCT scholarship from Portugal. Theorfeo-cinqa network CTQ2014-51912-REDC is kindly acknowledged.All calculations were carried out at Centro de Supercomputaciónde Galicia (CESGA)
DS Minerva
RD 24 abr 2026