RT Journal Article T1 Bleeding during tooth extraction in patients with chronic kidney disease: A cross‐sectional pilot study A1 Figueiredo, Marilia Andrade A1 Andrade, Natalia Silva A1 Blanco Carrión, Andrés A1 Medina, Janaina Braga A1 Gallottini, Marina A1 Ortega, Karem L. K1 Bleeding K1 Chronic kidney disease K1 End-stage renal disease K1 Haemodialysis K1 Nitrogenous compounds K1 Oral surgery K1 Tooth extraction AB Objective: This work measures the intra-operative bleeding in end-stage renal disease patients and assesses whether laboratory coagulation tests and nitrogenous compounds are related to a higher bleeding risk. Methods:Laboratory tests were performed on the day of surgery and some patients with thrombocytopenia and values above the normal levels of international normalised ratio (INR), thrombin time (TT) and activated partial thromboplastin time (aPTT) were identified. Results: Haemostatic time ranged from 2 to 35 min (mean of 8.51 min) after suture. Bleeding volume ranged from 0.02 to 67.06 mL (mean of 4.38 mL) and the bleeding volume per minute ranged from 0.05 to 2.10 mL/min (median of 0.6 mL/min). Only seven patients (16.27%) had abnormal bleeding (more than 0.6 mL/min). Spearman's coefficient showed weak correlations between bleeding volume (mL/min) and serum urea (r = 0.226), TT (r = 0.227), plasma urea (r = 0.148) and creatinine (r = 146), as well as very weak correlations with all other variables (r < 0.140) such as age, haemodialysis time, glycaemia, glycated haemoglobin, platelets, INR, aPTT and fibrinogen. Conclusion: It was not possible to associate any laboratory test or nitrogenous compounds present in the blood and saliva with an increased bleeding PB Wiley SN 1354-523X YR 2023 FD 2023 LK http://hdl.handle.net/10347/33194 UL http://hdl.handle.net/10347/33194 LA eng NO Figueiredo, M. A., Andrade, N. S., Blanco Carrión, A., Medina, J. B., Gallottini, M., & Ortega, K. L. (2023). Bleeding during tooth extraction in patients with chronic kidney disease: A cross-sectional pilot study. Oral Diseases, 00, 1–8. https://doi.org/10.1111/odi.14709 NO We wish to thank all the patients, family members and staff from all the units that participated in the study DS Minerva RD 24 abr 2026