RT Journal Article T1 Hard and soft tissue integration of immediate and delayed implants with a modified coronal macrodesign: Histological, micro-CT and volumetric soft tissue changes from a pre-clinical in vivo study A1 Sanz Martín, Ignacio A1 Vignoletti, Fabio A1 Nuñez, Javier A1 Permuy Mendaña, María A1 Muñoz Guzón, Fernando María A1 Sanz Esporrín, Javier A1 Fierravante, Ludovica A1 Shapira, Lior A1 Sanz Alonso, Mariano K1 Animal model K1 Dental implants K1 Histology K1 Immediate implant K1 Implant macrodesign K1 Micro-CT K1 Volumetric analysis AB Aim: To study the healing of peri-implant tissues around implants with a triangular coronal third (test) or cylindrical (control).Materials and Methods: In eight beagle dogs, immediate and delayed implants were placed. Test and control implants were randomly assigned and the hard and soft tissue healing was evaluated with histology and micro-CT analysis at 4 and 12 weeks. The soft tissue contour changes were assessed by image analysis software.Results: When measured at the implant shoulder level, the buccal crestal width (primary outcome assessed in mm) attained similar values in test and control implants. More apically (3 mm) test implants had greater buccal crestal width in delayed and immediate sites. For vertical soft and hard tissue measurements, no significant differences were found between Test and Control. Micro-CT evaluation of the buccal volume of interest showed less volume of implant component in T implants in all sites, although bone volume was not significantly different between T/C. Soft tissue contours were similar around T/C implants.Conclusion: Triangular implants showed similar percentage of osseointegration, buccal bone volume and soft tissue contours, although attaining greater buccal crestal bone width. No differences were found in regard to soft tissue dimensions and the position of the first bone-to-implant contact. PB Wiley SN 1600-051X SN 0303-6979 YR 2017 FD 2017 LK https://hdl.handle.net/10347/38983 UL https://hdl.handle.net/10347/38983 LA eng DS Minerva RD 23 abr 2026