RT Journal Article
T1 Development of a sensitive methodology for the analysis of chlorobenzenes in air by combination of solid-phase extraction and headspace solid-phase microextraction
A1 Barro Piñeiro, Ruth
A1 Ares, Sergio
A1 García Jares, Carmen María
A1 Llompart Vizoso, María del Pilar
A1 Cela Torrijos, Rafael
K1 Air analysis
K1 Solid-phase microextraction
K1 Solid-phase extraction
K1 Factorial design
K1 Headspace analysis
K1 Chlorobenzenes
K1 Organochlorine compounds
K1 Volatile organic compounds
AB In this study, a combination of solid-phase extraction (SPE) and solid-phase microextraction (SPME) has been used to determine chlorobenzenes in air. Analytes were sampled by pumping a known volume of air through a porous polymer (Tenax TA). Then, the adsorbent was transferred into a glass vial and SPME was performed. The quantification was carried out using gas chromatography (GC)–electron-capture detection or GC–MS. Several SPME coatings (100 μm poly(dimethylsiloxane) (PDMS), 75 μm Carboxen (CAR)–PDMS, 65 μm PDMS–divinylbenzene (DVB), 65 μm PDMS–DVB and 85 μm polyacrylate (PA) were evaluated, obtaining the highest responses with Carbowax (CW)– PDMS for the most volatile chlorobenzenes, and with PDMS–DVB or CW–DVB fibers for the semivolatile compounds. To optimize some other factors that could affect the SPME step, a factorial design was used. Kinetic studies of the SPME process were also performed. Concerning the SPE step, breakthrough was studied, showing that 2.5 m3 of air could be processed without losses of the most volatile compounds. The performance of the method was evaluated. External calibration, which does not require the complete sampling process, demonstrated to be suitable, obtaining good linearity (R2 > 0.99) for all chlorobenzenes. Recovery studies were performed at two concentration levels (4 and 40 ng/m3), obtaining quantitative recoveries (>80%). Limits of detection at the sub ng/m3 were achieved for all the target compounds.
PB Elsevier
YR 2004
FD 2004
LK http://hdl.handle.net/10347/32070
UL http://hdl.handle.net/10347/32070
LA eng
NO Barro, R., Ares, S., García-Jares, C., Llompart, M., Cela, R. (2004). Development of a sensitive methodology for the analysis of chlorobenzenes in air by combination of solid-phase extraction and headspace solid-phase microextraction. "Journal of Chromatography A", vol. 1045, 189-196
NO This research was supported by the projects BQU2003-02090 from CICYT Spanish Commission for Research and development (Ministerio de Ciencia y Tecnología) and PGIDIT04PXIC23701PN from Xunta de Galicia. R. Barro acknowledges the regional government Xunta de Galicia for her Doctoral grant.
DS Minerva
RD 24 abr 2026