RT Journal Article
T1 Lipidic lyotropic liquid crystals: insights on biomedical applications
A1 Blanco Fernández, Guillermo
A1 Blanco Fernandez, Bárbara
A1 Fernández Ferreiro, Anxo
A1 Otero Espinar, Francisco Javier
K1 Liquid crystals
K1 Drug delivery
K1 Imaging
K1 Tissue engineering
K1 Glycerol monooleate
AB Liquid crystals (LCs) possess unique physicochemical properties, translatable into a wide range of applications. To date, lipidic lyotropic LCs (LLCs) have been extensively explored in drug delivery and imaging owing to the capability to encapsulate and release payloads with different characteristics. The current landscape of lipidic LLCs in biomedical applications is provided in this review. Initially, the main properties, types, methods of fabrication and applications of LCs are showcased. Then, a comprehensive discussion of the main biomedical applications of lipidic LLCs accordingly to the application (drug and biomacromolecule delivery, tissue engineering and molecular imaging) and route of administration is examined. Further discussion of the main limitations and perspectives of lipidic LLCs in biomedical applications are also provided
PB Elsevier
YR 2023
FD 2023
LK http://hdl.handle.net/10347/30607
UL http://hdl.handle.net/10347/30607
LA eng
NO Advances in Colloid and Interface Science 313 (2023) 102867
NO This research was supported by the Spanish Ministry of Science, Innovation and Universities (RTI2018-099597-B-100). Instituto de Salud Carlos III (ISCIII)/ (PI20/00719, cofounded by European Union and JR18/00014) and by Xunta de Galicia (ED431C2021/26, IN607D2021/01)
DS Minerva
RD 3 may 2026