RT Journal Article
T1 Edible Chitosan/Acetylated Monoglyceride Films for Prolonged Release of Vitamin E and Antioxidant Activity
A1 Blanco Fernández, Bárbara
A1 Rial Hermida, María Isabel
A1 Álvarez Lorenzo, Carmen
A1 Concheiro Nine, Ángel Joaquín
K1 Packaging
K1 Films
K1 Biomedical applications
K1 Controlled release
K1 Antioxidant film
AB α-Tocopherol-loaded chitosan films for pharmaceutical applications and food packaging purposes were designed to attain prolonged antioxidant activity. The films were prepared according to an emulsification/casting-solvent process from dispersions containing chitosan at 1.0 and 1.5% (w/w), combining five different proportions of α-tocopherol (ranging from 0 to 40% (w/w) with respect to chitosan) and two acetylated monoglyceride (AM) : α-tocopherol weight ratios (1 : 1 or 4 : 1). AM is a safe, edible, fully hydrogenated palm-based oil that provided adequate distribution of α-tocopherol in the films. Humidity at equilibrium, puncture strength and puncture deformation decreased as the content in α-tocopherol increased; no relevant effect of cross-linking in a glutaraldehyde atmosphere was observed. Degree of swelling and α-tocopherol release were tested in hydroalcoholic medium that mimic the polarity of the skin and certain foods. The films behaved as superabsorbent and sustained the release for more than 5 days; after 20 days, the antioxidant activity of α-tocopherol in the release medium was in some cases still as higher as that of a freshly prepared solution. The greater the content in α-tocopherol, the slower the release in percentage was. AM exerted a protective effect on α-tocopherol, but when incorporated at too high proportion made the films to have an oily aspect. In sum, the chitosan films showed suitable features to be used as components of α-tocopherol sustained release formulations and long-term antioxidant packaging materials.
PB Wiley
SN 0021-8995
YR 2013
FD 2013-04-18
LK https://hdl.handle.net/10347/39489
UL https://hdl.handle.net/10347/39489
LA eng
NO Blanco-Fernandez, B., Rial-Hermida, M.I., Alvarez‐Lorenzo, C., & Concheiro, A. (2013). Edible chitosan/acetylated monoglyceride films for prolonged release of vitamin E and antioxidant activity. Journal of Applied Polymer Science, 129, 626-635.
DS Minerva
RD 30 abr 2026